Figure 1

Distribution of coding and noncoding sequence similarity between macaque and human. A histogram showing the degree of nucleotide sequence similarity between macaque and human for coding (blue) and noncoding (3' UTR, yellow) transcribed sequence. Sequences (n = 1,180) were selected that cross a well defined stop codon and that provide concurrent sampling of 150 bp of sequence both proximal and distal to the stop. The best human match for each macaque sequence was identified using MEGABLAST. The high-quality subset of these data (composed only of contiguous stretches of phred Q ≥ 20 bp, n = 633) is plotted for both coding (squares) and noncoding (diamonds) sequence.