Genomic analysis of metabolic pathway gene expression in mice

Table 3 Nineteen candidate genes with cis-eQTL in chromosome 19 locus

cis-QTL gene symbol	Physical location of the gene (Mb)	Estimated physical location of the eQTL (Mb)	Correlation with subcutaneous fat mass
RIKEN cDNA 9530025L08	29.5	48.6	-0.29*
Cyp2c40 ^†	39.1	40.6	0.24
Col17a1	47.0	40.6	-0.25*
Scd2	43.6	40.6	-0.19
Slk	46.9	41.8	-0.07
Cyp2c37	39.3	37.0	0.32*
Cyp2c39 ^†	38.8	40.6	0.03
Gsto1	47.2	41.8	0.26*
Rnf134	46.4	48.6	0.05
Cutc	43.1	39.4	0.25*
Cpn1	43.3	39.4	0.28*
Cnnm1	42.8	46.2	0.27*
Acsl5	54.6	37.0	0.30*
RIKEN cDNA 1810018P12	32.0	35.7	0.24
Pik3ap1	40.6	39.4	-0.07
RIKEN cDNA 0610010D20	41.4	41.8	0.10
RIKEN cDNA 4833409A17	42.1	40.6	-0.21
RIKEN cDNA 4930538D17	45.7	38.2	-0.22
RIKEN cDNA 5730455O13	37.4	40.6	0.14

*Significant correlation of transcript levels with subcutaneous fat mass (p < 0.05). ^†The two genes that solely contributed to the significant LOD score of the fatty-acid metabolism and γ-hexachlorocyclohexane degredation principal components to chromosome 19 (see text for details).

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