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Table 2 Chromosomal loci with significant enrichment for obesity-associated pathway gene eQTLs relative to eQTLs of all 4,670 most differentially expressed genes

From: Genomic analysis of metabolic pathway gene expression in mice

Chromosome (cM)

Total number of genes with eQTL

Expected number of pathway genes with eQTL

Observed number of pathway genes with eQTL

p-value

Adjusted p-value

3 (80-100)

25

1

9

9.24 E-11

1.68 E-08

6 (30-50)

836

14

28

8.05 E-05

1.47 E-02

16 (0-20)

431

7

21

3.44 E-06

6.27 E-04

19 (20-40)

891

15

38

1.45 E-09

2.63 E-07

19 (30-50)

709

12

31

6.77 E-08

1.23 E-05