| |
Physiological fitness*
|
Competitive fitness†
| |
Physiological fitness
|
Competitive fitness
|
|---|
|
Mutants
|
MM
|
YPD
|
YPD
|
Mutants
|
MM
|
YPD
|
YPD
|
|---|
|
Reference strain
|
1
|
1
|
1
| | | | |
|
adh1/YOL086C
|
0.47
|
0.57
|
0.79
|
mdh2/YOL126C
|
0.89
|
0.98
|
1.01
|
|
adh3/YMR083W
|
0.92
|
0.87
|
0.98
|
mdh3/YDL078C
|
1.00
|
0.96
|
1.01
|
|
ald5/YER073W
|
1.02
|
0.94
|
1
|
mls1/YNL117W
|
1
|
0.98
|
1
|
|
ald6/YPL061W
|
0.34
|
0.87
|
0.9
|
oac1/YKL120W
|
0.71
|
0.94
|
1.01
|
|
cox5A/YNL052W
|
0.63
|
0.91
|
1
|
pck1/YKR097W
|
1
|
0.96
|
1
|
|
ctp1/YBR291C
|
0.91
|
1
|
0.97
|
pda1/YER178W
|
0.41
|
0.98
|
1
|
|
dal7/YIR031C
|
0.94
|
0.85
|
1
|
pgm1/YKL127W
|
0.82
|
0.94
|
1
|
|
fum1/YPL262W
|
0.52
|
0.62
|
0.93
|
pgm2/YMR105C
|
0.90
|
1
|
1
|
|
gnd1/YHR183W
|
0
|
0.87
|
1.01
|
rpe1/YJL121C
|
0.33
|
0.94
|
0.88
|
|
gnd2/YGR256W
|
0.83
|
0.98
|
1
|
sdh1/YKL148C
|
0.72
|
0.94
|
1
|
|
gcv2/YMR189W
|
0.92
|
0.94
|
1
|
ser33/YIL074C
|
0.92
|
0.94
|
1.01
|
|
gly1/YEL046C
|
0.79
|
0.74
|
0.87
|
sfc1/YJR095W
|
0.84
|
0.96
|
1.01
|
|
gpd1/YDL022W
|
1
|
0.98
|
0.84
|
sol1/YNR034W
|
0.91
|
1
|
1.02
|
|
icl1/YER065C
|
1
|
1
|
1
|
sol2/YCRX13W
|
0.99
|
0.98
|
1
|
|
idp1/YDL066W
|
0.92
|
0.94
|
1.03
|
sol3/ YHR163W
|
0.71
|
0.94
|
1
|
|
idp2/YLR174W
|
0.86
|
0.96
|
0.95
|
sol4/ YGR248W
|
0.95
|
0.91
|
1.01
|
|
lsc1/YOR142W
|
1.05
|
0.93
|
1
|
tal1/ YLR354C
|
0.89
|
0.94
|
1
|
|
mae1/YKL029C
|
1.01
|
0.96
|
1
|
YGR043C
|
0.92
|
0.87
|
1.02
|
|
mdh1/YKL085W
|
0.72
|
0.91
|
1
|
zwf1/YNL241C
|
0.38
|
0.96
|
ND
|
- *Physiological fitness is defined as the maximal specific growth rate of a mutant normalized to the reference strain CEN.PK 113-7D ho :: kanMX4. The average from triplicate experiments is shown. The standard deviation was generally below 0.05. †From Steinmetz et al. [20]. ND, not detected.
