Table 1 Genes included in the synthetic lethality matrix
ORF | Gene | Identification | Genotype used in this study |
|---|---|---|---|
F17A2.5 | ceh-40 | Homeodomain protein (Extradenticle ortholog) | ceh-40(ok740) X |
K10B4.6 | cwn-1 | Putative Wnt ligand | cwn-1(ok546) II |
D1081.2 | unc-120 | MADS domain TF | unc-120(st364) I |
B0304.1 | hlh-1 | bHLH TF | hlh-1(cc561) II |
C44C10.8 | hnd-1 | Hand bHLH TF | hnd-1(q740) X |
F35G12.6 | mab-21 | Highly conserved novel protein | mab-21(bx53)III; him-5(e1490)V |
F11C1.6 | nhr-25 | Nuclear hormone receptor | +/szT1 [lon-2(e678)] I; nhr-25(jm2389)/szT1 X |
Y75B8A.2 | nob-1 | Homeodomain TF (posterior Hox paralog) | nob-1(ct223) dpy-18(e364) unc-25(e156) III; eDp6 (III;f) |
K02B9.4 | elt-3 | GATA TF | elt-3(gk121) X |
T07C4.2 | tbx-8 | T-box TF (Brachyury) | tbx-8(ok656) III |
M142.4 | vab-7 | Homeobox TF (even-skipped subfamily) | vab-7(e1562) III |
T07C4.6 | tbx-9 | T-box TF (Brachyury) | Mutant not available |
C55C2.1 | Â | Zinc-finger TF | Mutant not available |
C38D4.6 | pal-1 | Homeobox TF (cad subfamily) | pal-1(ct224) dpy-17(e164) ncl-1(e1865) unc-36(e251) III; sDp3(f:III); lin-2(e1309) X |
W09C2.1 | elt-1 | GATA TF | elt-1(zu180) unc-43(e408)/unc-24(e138) dpy-20(e1282) IV |
F18A1.2 | lin-26 | Zinc-finger TF | lin-26(n156) II |
T28F12.2 | unc-62 | Meis-class homeodomain (Homothorax ortholog) | unc-62(e644) V |
C28C12.7 | spp-10 | Predicted prosaposin | Mutant not available |
R02D3.1 | Â | Dehydrogenase | Mutant not available |
C09D4.2 | Â | Uncharacterized | Mutant not available |
R07C3.11 | Â | Uncharacterized | Mutant not available |
T22B7.3 | Â | Uncharacterized | Mutant not available |
C46H11.2 | Â | Uncharacterized | Mutant not available |
ZK1307.1 | Â | Uncharacterized | Mutant not available |
C01G6.1 | aqp-2 | Aquaporin | Mutant not available |
T27D12.1 | Â | Sodium/phosphate transporter | Mutant not available |