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Table 1 Genetic interactions of mutant genes with biological processes

From: Derivation of genetic interaction networks from quantitative phenotype data

Gene Form* Interaction Biological process -log10P
PBS2 null Additive Signal transduction 2.99
PBS2 null Additive Small gtpase mediated signal transduction 2.96
STE12 gf Single-nonmonotonic to Protein targeting 2.87
STE11 da Noninteractive Cell cycle 2.73
PHD1 gf Hypostatic to Invasive growth 2.68
PDE2 null Noninteractive Protein amino acid phosphorylation 2.56
HSL1 null Suppressed by Cell wall organization and biogenesis 2.52
STE20 gf Single-nonmonotonic to Protein targeting 2.31
EGT2 null Conditioned by Invasive growth 2.30
ISW1 null Suppresses Small gtpase mediated signal transduction 2.30
CLB1 null Noninteractive Protein metabolism 2.30
STE11 da Suppresses Cell surface receptor linked signal transduction 2.28
BEM1 gf Conditioned by Nucleobase, nucleoside, nucleotide and nucleic acid metabolism 2.25
PBS2 null Additive Ras protein signal transduction 2.24
PBS2 null Additive Sporulation 2.24
TEC1 gf Synthetic Intracellular signaling cascade 2.19
IPK1 null Additive M phase 1.95
TEC1 null Epistatic to Metabolism 1.94
TEC1 gf Conditioned by Carbohydrate metabolism 1.94
TEC1 gf Conditioned by Ras protein signal transduction 1.94
BUD4 null Noninteractive Establishment of cell polarity 1.94
HMS1 null Noninteractive Protein amino acid phosphorylation 1.83
YGR045C null Noninteractive Protein amino acid phosphorylation 1.83
  1. *gf, gain-of-function; da, dominant-active.