Table 2 Comparison of selenoproteins identified in the Sargasso Sea database and in the combined set of completely sequenced prokaryotic genomes
Prokaryotic selenoprotein family | Sequences in the Sargasso Sea database | Sequences in completely sequenced prokaryotic genomes | ||
|---|---|---|---|---|
| Â | Selenoprotein | Cys homolog | Selenoprotein | Cys homolog |
Known selenoproteins detected in the Sargasso Sea dataset | ||||
SelW-like protein | 48 | 7 | 4 | 20 |
Peroxiredoxin | 43 | Widespread* | 1 | Widespread |
Proline reductase PrdB | 42 | 1 | 1 | 5 |
Selenophosphate synthetase | 28 | 23 | 16 | 22 |
Prx-like protein | 22 | 4 | 2 | 6 |
Thioredoxin | 11 | Widespread | 2 | Widespread |
Formate dehydrogenase alpha chain | 8 | Widespread | 40 | Widespread |
Glutathione peroxidase | 5 | Widespread | 1 | Widespread |
Glycine reductase selenoprotein A | 1 | 0 | 5 | 0 |
Glycine reductase selenoprotein B | 1 | 1 | 5 | 2 |
New selenoproteins detected in the Sargasso Sea dataset | ||||
AhpD-like protein | 27 | Widespread | 0 | Widespread |
Arsenate reductase | 14 | Widespread | 0 | Widespread |
Molybdopterin biosynthesis MoeB protein | 11 | Widespread | 0 | Widespread |
Glutaredoxin | 10 | 17 | 1 | Widespread |
DsbA-like protein | 9 | Widespread | 0 | Widespread |
Glutathione S-transferase | 4 | Widespread | 0 | Widespread |
Deiodinase-like protein | 4 | 6 | 0 | 0 |
Thiol-disulfide isomerase-like protein | 4 | Widespread | 0 | Widespread |
CMD domain-containing protein | 4 | 14 | 0 | 5 |
Hypothetical protein 1 | 4 | 7 | 0 | 5 |
Rhodanase-related sulfurtransferase | 3 | Widespread | 0 | Widespread |
OsmC-like protein | 3 | 10 | 0 | 17 |
DsrE-like protein | 2 | 3 | 1 | 9 |
DsbG-like protein | 1 | Widespread | 1 | Widespread |
NADH:ubiquinone oxidoreductase | 1 | Widespread | 0 | Widespread |
Known selenoproteins not detected in the Sargasso Sea dataset | ||||
Formylmethanofuran dehydrogenase | 0 | Widespread | 4 | Widespread |
F420-reducing hydrogenase alpha subunit | 0 | 4 | 4 | Widespread |
F420-reducing hydrogenase, delta subunit | 0 | 1 | 3 | Widespread |
Methylviologen-reducing hydrogenase | 0 | 3 | 3 | Widespread |
Heterodisulfide reductase | 0 | 0 | 4 | 23 |
HesB-like protein | 0 | 2 | 7 | 2 |
Total | 310 | Â | 105 | Â |