Multiple sequence alignments of new selenoproteins and their Cys homologs. The alignments show Sec-flanking regions in detected proteins. Both selenoprotein sequences detected in the Sargasso Sea database and their Cys-containing homologs present in indicated organisms are shown. Conserved residues are highlighted. Predicted Sec (U) and the corresponding Cys (C) residues in other homologs are shown in red and blue background, respectively. Sequence alignments were generated with ClustalW and shaded by BoxShade v3.21.