From: Quantitative genomics of starvation stress resistance in Drosophila
Probe set | Significant* | Gene | Location | Molecular function | Biological process | Cellular location |
---|---|---|---|---|---|---|
151378 | S, L, r | mitochondrial ribosomal protein L33 | 4B6 | Structural constituent of ribosome | Protein biosynthesis | Mitochondrial large ribosomal subunit |
151504 | L | no receptor potential A | 4C1 | 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase; phospholipase C | Olfaction; response to abiotic stimulus | inD signaling complex; membrane fraction; rhabdomere |
153437 | S, T, L, r | yippee interacting protein 2 | 30E4 | Acetyl-CoA C-acyltransferase | Fatty acid beta oxidation | Mitochondrion |
146142 | S, T, L, r | Selenophosphate synthetase 2 | 31D9 | Selenide, water dikinase; purine nucleotide binding | Selenocysteine biosynthesis | Â |
143984 | S, T, S × T, L, L × S | Accessory gland-specific peptide 32CD | 32D1 | Hormone | Negative regulation of female receptivity, post-mating | Extracellular |
141745 | S, L, L × S, L × T, r | Phosphoethanolamine cytidylyltransferase | 34A9 | Ethanolamine-phosphate cytidylyltransferase | ethanolamine and derivative metabolism; phospholipid metabolism |  |
146347 | S, L, L × S, L × T, L × S × T | centaurin gamma 1A | 34D6-E2 | ARF GTPase activator | G-protein-coupled receptor protein signaling pathway; small GTPase mediated signal transduction | Nucleus |
153741 | L × T | centaurin gamma 1A | 34D6-E2 | ARF GTPase activator | G-protein coupled receptor protein signaling pathway; small GTPase mediated signal transduction | Nucleus |
143402 | S, L, L × S, r | vasa | 35C1 | RNA helicase activity; nucleic acid binding; ATP dependent helicase | Dorsal appendage formation; oogenesis; pole plasm RNA localization; pole plasm assembly | Polar granule |
152721 | T, L, L × T, r | Imaginal disc growth factor 1 | 36A1 | Imaginal disc growth factor activity; NOT chitinase activity; hydrolase activity, hydrolyzing N-glycosyl compounds | Cell-cell signaling;signal transduction | Extracellular |
154661 | S, L | midway | 36B1-2 | Sterol O-acetyltransferase; diacylglycerol O-actyltransferase | Cholesterol metabolism; triacylglycerol biosynthesis | Â |
152756 | S, L, r | Arrestin 1 | 36D3 | Metarhodopsin binding | G-protein coupled receptor protein signaling pathway; deactivation of rhodopsin mediated signaling; endocytosis; intracellular protein transport; metarhodopsin inactivation | Membrane fraction; rhabdomere |
143876 | S, L | Galactose-specific C-type lectin | 37D6 | Galactose binding; sugar binding; receptor | Defense response | Â |
146555 | S, T, S × T, L, L× S | Serine protease inhibitor 3 | 38F2 | Serine-type endopeptidase inhibitor | Proteolysis and peptidolysis |  |
146592 | S, T, S × T, L× T, L× S× T | no mechanoreceptor potential B | 39E2 |  | NOT flagellum biogenesis; perception of sound; sensory cilium biogenesis |  |
143709 | S, T, L, r | Troponin C at 41C | 41E5 | Calcium ion binding; calmodulin binding | Calcium-mediated signaling; muscle contraction | Â |
143127 | S, T, L, L × T | Cytochrome P450-6a2 | 42C8-9 | Electron transporter activity; oxidoreductase | Response to insecticide; steroid metabolism | Membrane; microsome |
146718 | S, T, L × T | Tetraspanin 42Er | 42F1 | Receptor signaling protein | Ectoderm development; neurogenesis; transmission of nerve impulse | Integral to membrane |
142222 | T, L, L × T | Cytochrome P450-9b2 | 42F3 | Electron transporter activity; oxidoreductase |  | Membrane; microsome |
143830 | S, L | Calcineurin B2 | 43E16 | Calmodulin binding; calcium-dependent protein serine/threonine phosphatase, regulator; calcium ion binding | Calcium-mediated signaling; cell homeostasis | Calcineurin complex |
141501 | S, T, L, r | Proteasome alpha6 subunit | 43E18 | Proteasome endopeptidase | Proteolysis and peptidolysis | 20S core proteasome complex |
143303 | S, T, L, r | photorepair | 43E18 | Deoxyribodipyrimidine photolyase; nucleic acid binding | DNA repair | Â |
146780 | S, L × T, L × S × T, r | Sep5 | 43F8 | Structural constituent of cytoskeleton; small monomeric GTPase | Cytokinesis; mitosis | Septin ring |
143780 | L, L × S | Cytochrome P450-4e1 | 44D1 | Electron transporter activity; oxidoreductase |  | Membrane; microsome |
152113 | S, T, L × S, r | anachronism | 45A1 |  | Suppression of neuroblast proliferation | Extracellular |
143554 | S, L | trp-like | 46B2 | Calcium channel; calmodulin binding; light-activated voltage-gated calcium channel; store-operated calcium channel | Calcium ion transport | Plasma membrane; rhabdomere |
146946 | S, T, L × T, r | Peroxiredoxin 2540 | 47A7 | Antioxidant; peroxidase; non-selenium glutathione peroxidase | Defense response; oxygen and reactive oxygen species metabolism |  |
143603 | T, L | gammaTrypsin | 47F4 | NOT serine-type endopeptidase | Proteolysis and peptidolysis | Extracellular |
143602 | T, L | betaTrypsin | 47F4 | Trypsin | Proteolysis and peptidolysis | Extracellular |
143604 | T, L | gammaTrypsin | 47F4 | NOT serine-type endopeptidase | Proteolysis and peptidolysis | Extracellular |
143624 | T, L × T | epsilonTrypsin | 47F4 | Trypsin | Proteolysis and peptidolysis | Extracellular |
153279 | S, T, L, r | Translocon-associated protein d | 47F7 | Signal sequence receptor | Protein-ER retention | Signal sequence receptor complex; translocon |
141563 | L | acyl-Coenzyme A oxidase at 57D proximal | 57E1 | Acyl-CoA oxidase; palmitoyl-CoA oxidase | Fatty acid beta-oxidation | Peroxisome |
151902 | S, T, L, r | jitterbug | 59A3 | Actin binding; structural constituent of cytoskeleton | Cytoskeleton organization and biogenesis | Â |
154177 | S, L, L × S, r | Cyclin B | 59B2 | Cyclin-dependent protein kinase, regulator | Cytokinesis; mitotic anaphase B; mitotic chromosome movement | Nuclear cyclin-dependent protein kinase holoenzyme complex; pole plasm |
143203 | S, T, L, r | inactivation no afterpotential D | 59B3 | Structural molecule; calmodulin binding; myosin binding; receptor signaling complex scaffold | Cell surface receptor linked signal transduction; phototransduction; protein targeting | inaD signaling complex; rhabdomere |
151517 | L | Phosphotidylinositol 3 kinase 59F | 59E4-F1 | Phosphatidylinositol 3-kinase; phosphoinositide 3-kinase | Endocytosis; phosphoinositide phosphorylation; protein targeting | Phosphoinositide 3-kinase complex, class III |
151830 | S, T, L, L × T, r | lethal (2) essential for life | 59F6 | Heat shock protein | Defense response; protein folding; response to stress |  |
144140 | T, L, r | Mitochondrial phosphate carrier protein | 70E1 | Phosphate transporter; carrier | Phosphate metabolism; phosphate transport | Mitochondrial inner membrane |
151748 | L, L × T, r | Cyclic-AMP response element binding protein A | 71E1 | DNA binding; RNA polymerase II transcription factor; transcription factor | Salivary gland morphogenesis; transcription from Pol II promoter | Nucleus |
153226 | S, T, L | Argonaute 2 | 71E1 | Translation initiation factor; protein binding | RNA interference; translational initiation | RNA-induced silencing complex |