Figure 7
From: Promoter features related to tissue specificity as measured by Shannon entropy
The distribution of TATA box and initiator element (Inr) in pancreas-specific genes. One hundred and sixty pancreas genes were divided into bins according to their Q-value. Genes that have a TATA box, an initiator with the motif YYANWYY, both, or none of these two motifs, are shown. (a) Absolute numbers of genes with core promoter motifs. Red bars, TATA only; blue bars, TATA and Inr; green bars, Inr only; purple bars, none. The p-values for pairwise comparison of distributions (TATA/total) are given below the graph. P-values were calculated for the sum of genes with TATA box (with and without initiator). (b) Results from (a) plotted as fractions of genes with each motif status within a bin. (c) Number of TATA boxes found in orthologous human and mouse gene pairs. Statistical significance of differences between Q bins are indicated.