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Figure 2 | Genome Biology

Figure 2

From: Promoter features related to tissue specificity as measured by Shannon entropy

Figure 2

Distributions of H and Q for different data sources and tissues. (a) Distribution of H as estimated from GNF-GEA (red line) and DoTS (blue line). The DoTS curve was generated from genes with at least six ESTs. (b) Correlation of H estimates from GNF-GEA and DoTS. Genes with at least 30 ESTs are shown in red; those with more than 100 ESTs in blue. (c) Cumulative distribution of Q values for selected mouse tissues and the average for all 39 tissues. Mammary gland, liver, muscle and the amygdala have decreasing numbers of highly tissue-specific genes. Liver has a very large number of relatively specific genes. All distributions peak at 2 log2(39) = 10.6 bits and have a tail at high Q (not shown) that corresponds to genes that are ubiquitously expressed except in the tissue of interest.

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