Pathway | Enzyme/Protein name | Accession number | Number | Cluster |
---|---|---|---|---|
Urea cycle and arginine-citrulline cycles | Arginine succinate synthase | NP_031520 | 128 | 1/10 |
Phosphatidylinositol | Phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 | XP_127550 | 446 | 7 |
 | Myoinositol 1-phosphate synthase A1 | NP_076116 | 156 | 8 |
Cholesterol biosynthesis/keto-body synthesis | 3-hydroxy-3-methylglutaryl-CoA synthase 1 | NP_666054 | 178 | 4 |
 | 3-hydroxy-3-methylglutaryl-CoA reductase | XP_127496 | 619 | 12 |
Triglyceride hydrolysis (fatty acid assimilation) | Lipoprotein lipase (LPL) | NP_032535 | 14 | 6 |
β-Oxidation | Acetyl-CoA dehydrogenase (Acad) | NP_780533 | 61 | 6 |
 | Acetyl-CoA dehydrogenase, medium chain (Acadm) | NP_031408 | 153 | 6/9 |
 | Isovaleryl-CoA dehydrogenase (Acad) | Mm.6635 | 510 | 6 |
 | Acyl-CoA dehydrogenase, short/branched chain (Acadsb) | NP_080102 | 220 | 9 |
Triglyceride metabolism | Adipose triglyceride lipase (Pnpla2/Atgl) | NP_080078 | 157 | 6 |
CoA biosynthesis | Pantothenate kinase 3 | NP_666074 | 140 | 6 |
Anaplerotic processes | Pyruvate carboxylase | NP_032823 | 149 | 6 |
Branched chain amino acid metabolism (AKA metabolism) | Branched chain ketoacid dehydrogenase E1, α polypeptide | NP_031559 | 193 | 3/9 |
Methylation | S-adenosylhomocysteine hydrolase | NP_057870 | 66 | 8 |
 | Methionine adenosyltransferase II, α | NP_663544 | 350 | 2 |
Unsaturated fatty acid biosynthesis | Stearoyl-CoA desaturase 1 | NP_033153 | 305 | 6 |
Nucleotide metabolism | Xanthine dehydrogenase | NP_035853 | 361 | 2 |
Taurin biosynthesis | Cysteine dioxygenase | NP_149026 | 271 | 7 |
NH4 + metabolism/glutamate | Glutamate-ammonia ligase (glutamine synthase) | NP_032157 | 318 | 7 |
Glycolysis | Pyruvate kinase 3 | NP_035229 | 247 | 8 |
Substrate cycle (glycolysis/gluconeogenesis) | Fructose bisphosphatase 2 | NP_032020 | 175 | 9 |
Nucleotide biosynthesis | Deoxycytidine kinase | NP_031858 | 363 | 8 |
 | Ribonucleotide reductase M2 | NP_033130 | 448 | 8 |
Pentose phophate shunt | Hexose-6-phosphate dehydrogenase (AI785303) | XP_181411 | 533 | 9 |
NAD(P) biosynthesis | Pre-B-cell colony-enhancing factor | NP_067499 | 327 | 9 |
Polyamine biosynthesis | Ornithine decarboxylase, structural | NP_038642 | 212 | 10 |
Tetrahydrobiopterin biosynthesis | GTP cyclohydrolase 1 | NP_032128 | 259 | 10 |
Purin biosynthesis | Phosphoribosyl pyrophosphate amidotransferase | NP_742158 | 287 | 11 |
Asparagine biosynthesis | Asparagine synthetase | NP_036185 | 109 | 12 |
Long chain fatty acids | ELOVL family member 6, elongation of long chain fatty acids | NP_569717 | 162 | 12 |
Serine biosynthesis | Phosphoserine phosphatase | NP_598661 | 261 | 12 |
Gluconeogenesis | PEPCK 2 (Riken 9130022B02) | NP_083270 | 393 | 12 |
Prostaglandin E biosynthesis | Prostaglandin E synthase (ri|2410099E23; ri|9230102G02) | ri|2410099E23 ri|9230102G02 | 539 540 | 9 |