Table 8 Most statistically significantly regulated functional groups in the fetal heart tissues based on their p values from t tests
From: Primary and secondary transcriptional effects in the developing human Down syndrome brain and heart
GO group | GO identifier | Number of probe sets | p value | Mean of GO group | Mean of non-group members |
|---|---|---|---|---|---|
Mitochondrion | GO:0005739 | 446 | 6.61E-16 | 0.04 | -0.01 |
Monovalent inorganic cation transporter activity | GO:0015077 | 86 | 4.27E-10 | 0.07 | -0.01 |
Defense response | GO:0006952 | 485 | 2.29E-08 | -0.06 | -0.01 |
NADH dehydrogenase activity | GO:0003954 | 31 | 5.25E-06 | 0.07 | -0.01 |
Intracellular transport | GO:0046907 | 428 | 2.34E-05 | 0.02 | -0.01 |
Cell-cell signaling | GO:0007267 | 201 | 1.02E-04 | -0.07 | -0.01 |
Mitochondrial inner membrane | GO:0005743 | 74 | 1.66E-04 | 0.04 | -0.01 |
Cell surface receptor linked signal transduction | GO:0007166 | 594 | 1.74E-04 | -0.04 | -0.01 |
Integral to plasma membrane | GO:0005887 | 948 | 1.95E-04 | -0.03 | -0.01 |
Extracellular region | GO:0005576 | 215 | 2.40E-04 | -0.06 | -0.01 |
Membrane fusion | GO:0006944 | 14 | 4.68E-04 | 0.06 | -0.01 |
DNA metabolism | GO:0006259 | 322 | 8.13E-04 | 0.02 | -0.01 |
Regulation of muscle contraction | GO:0006937 | 28 | 9.33E-04 | 0.08 | -0.01 |
Single-stranded DNA binding | GO:0003697 | 45 | 1.38E-03 | 0.06 | -0.01 |
Electron carrier activity | GO:0009055 | 12 | 1.41E-03 | 0.08 | -0.01 |