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Table 1 Polyadenylation-related protein factors

From: Biased alternative polyadenylation in human tissues

 

Gene name

Gene ID*

U95Av2 probe-sets

U133A probe-sets

1

CPSF-160, cleavage and polyadenylation specificity factor 1, 160 kDa

29894

33132_at

201638_s_at

201639_s_at

33132_at

2

CPSF-100, cleavage and polyadenylation specificity factor 2, 100 kDa

53981

NA

NA

3

CPSF-73, cleavage and polyadenylation specificity factor 3, 73 kDa

51692

NA

NA

4

CPSF-30, cleavage and polyadenylation specificity factor 4, 30 kDa

10898

35743_at

206688_s_at

5

CFI25, cleavage factor Im, 25 kDa

11051

39142_at

202697_at

213461_at

6

CFI68, cleavage factor Im, 68 kDa

11052

35757_at

202469_s_at

202470_s_at

7

hFip1, Saccharomyces cerevisiae Fip1p like

81608

NA

221007_s_at

8

CstF50, cleavage stimulatory factor subunit 1, 50 kDa

1477

32723_at

202190_at

32723_at

9

CstF-64, cleavage stimulatory factor subunit 2, 64 kDa

1478

40334_at

204459_at

10

CstF-77, cleavage stimulatory factor subunit 3, 77 kDa

1479

41183_at

203947_at

11

Ï„CstF-64, cleavage stimulatory factor subunit 2, 64 kDa, tau variant

23283

41248_at

212901_s_at

212905_at

12

CFIIA, HEAB, ATP/GTP binding protein, component of CFIIAm [52]

10978

33149_at

204370_at

13

PCF11, pre-mRNA cleavage complex II protein [53]

51585

41665_at

203378_at

14

PABPII, poly(A) binding protein, nuclear 1

8106

39050_at

201544_x_at

201545_s_at

213046_at

15

Symplekin [1,2]

8189

32402_s_at

32402_s_at

202339_at

16

HNRPF, heterogeneous nuclear ribonucleoprotein F [5]

3185

38071_at

201376_s_at

17

HNRPH, heterogeneous nuclear ribonucleoprotein H1 (H) [6]

3187

41292_at

201031_s_at

213470_s_at

213472_at

18

HNRPH', heterogeneous nuclear ribonucleoprotein H2 (H') [6]

3188

41131_f_at

41132_r_at

201132_at

19

U2AF65, U2 small nuclear RNA auxiliary factor2 [7]

11338

32556_at

218381_s_at

218382_s_at

20

U1A, U1 small nuclear ribonucleoprotein polypeptide A [8,10]

6626

40842_at

201770_at

21

PC4, transcriptional coactivator [3]

10923

36171_at

212857_x_at

214512_s_at

221727_at

22

Similar to HSPC182 protein, human HomoloGene of yeast Ssu72 [4]

286528

NA

NA

23

SRp20 [12]

6428

351_f_at

40457_at

202899_s_at

208672_s_at

208673_s_at

24

PTB, polypyrimidine tract binding protein, also known as hnRNP I [11]

5725

40593_at

202189_x_at

211270_x_at

211271_x_at

212015_x_at

212016_s_at

216306_x_at

25

nPTB, polypyrimidine tract binding protein 2

58155

NA

218683_at

26

PAP, poly(A) polymerase

10914

34855_at

209388_at

212718_at

212720_at

215374_at

222035_s_at

  1. References supporting the role of a given factor in mRNA polyadenylation can be found in review articles Proudfoot et al. [54], Zhao et al. [21], and Edwalds-Gilbert et al. [15], if not otherwise noted. Some genes do not have corresponding probe sets on a microarray, as indicated by NA. *Gene IDs are NCBI Entrez Gene IDs [55].