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Table 2 Identification of splice junctions

From: A computational investigation of kinetoplastid trans-splicing

 

Known trans-splicing regions

Known coding regions

Predicted splice sites

True positive

False positive

 

17

2.5

 

(10-22)

(0-4)

Predicted nonsplice sites

False negative

True negative

 

4.5

13.9

 

(1-8)

(11-16)

 

Sensitivity: 0.80

Specificity: 0.85

 

(0.71-0.93)

(0.75-1.00)

 

Accuracy: 0.82

 

(0.74-0.93)

  1. The overall performance of the method in identifying splice junctions was determined by comparing the number of known splice junctions that were identified by the method in known trans-splicing regions versus those in known coding regions. These results are from tenfold cross-validation, and each test dataset had on average 21.5 known trans-splicing regions and 16.4 known coding regions.