Genome-wide gene expression in response to parasitoid attack in Drosophila

Table 1 Putative regulatory motifs that were over-represented in the eight major clusters of differentially expressed genes

Motif	Time point (hours)	Cluster, raw score and significance^†
Relish/NF-κB-like	1, 3, 48	Cluster 1	8.54	P < 0.001
		Cluster 2	8.01	P = 0.002
		Cluster 11	5.09	P < 0.006
		Cluster 12	17.3	P < 0.001
		Cluster 14	12.4	P = 0.001
serpent/GATA-like	1, 2, 3, 6, 72	Cluster 1	7.13	P < 0.001
		Cluster 2	21.2	P < 0.001
		Cluster 9	17.5	P < 0.001
		Cluster 10	8.43	P = 0.009
		Cluster 12	10.5	P = 0.001
STAT	-	Cluster 2	4.88	P < 0.001
		Cluster 12	4.83	P < 0.001
TATA-like	72	Cluster 1	5.57	P = 0.001
		Cluster 9	13.9	P < 0.001
		Cluster 10	6.21	P = 0.002
CCARCAGRCCSA	1, 2, 3, 6	Cluster 2	56.1	P < 0.001
		Cluster 12	27.8	P < 0.001
		Cluster 14	14.3	P = 0.001
CAWTSKATTC	2, 3	Cluster 2	17.5	P < 0.001
		Cluster 14	8.39	P = 0.008
AMTCAGT	2, 3, 6, 12, 72	Cluster 2	16.6	P < 0.001
		Cluster 12	10.9	P < 0.001
		Cluster 14	8.99	P = 0.001

Putative motifs were identified as described in the text. The table shows the motifs identified, the time points at which they were significantly associated, and the clusters in which they appeared. For each cluster we give the raw score (a measure of the average occupancy in a set of sequences) and the associated significance value. ^†Only for clusters with more than five genes.

ISSN: 1474-760X