Figure 2

CNG methylation targets of epigenetic silencing components. (a) Venn diagram summaries of positive loci using random-PCR arrays in cmt3, kyp, drm1/2 and ago4 mutant backgrounds. Loci were scored as positive if methylation was significantly changed in the indicated mutant relative to the Ler wild-type background. (b) Venn diagram summaries of positive loci using gene-oligo arrays, where cmt3, kyp, drm1/2 and ago4 were in a Ler (clk-st) and crm3 drm1/2 was in a Ws wild-type background. Gene-oligo and random-PCR datasets of targets are available with a graphical interface for browsing and for downloading [25]. (c) Table showing the number of positives and overlaps for each mutant class. Mutants are color coded for clarity in the Venn diagrams.