Figure 4

NPC and NPCa protein evloutionary rates within lineages. Comparison of the evolutionary rates of three lineages for several NPC and NPCa proteins, calculated for a marker as the average distance between species of a particular lineage: (a) metazoa in red; (b) fungi in blue; and (c) green plants in green. The evolutionary rate for a marker corresponds to the average distance estimated between species of a given lineage. The evolutionary rates were mapped onto the (d) metazoan, (e) fungi and (f) green plant NPC structures with a color code: green, slowly evolving marker (average distance < 1); yellow, marker evolving at an average rate (1 < average distance < 2); red, rapidly evolving marker (2 < average distance < 3); dark red, very rapidly evolving marker (average distance > 3).