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Table 2 Numbers of genes that are differentially expressed

From: Changes in gene expression during the development of mammary tumors in MMTV-Wnt-1transgenic mice

Comparisons

Number of genes differentially expressed

Tissue A (number of samples)

Tissue B (number of samples)

Total

Up

Down

WntH (7)

VMG (5)

584

121

463

WntT (23)

WntH (7)

388*

112

276

WntT (23)

NeuT (12)

1,296

624

672

NeuT (12)

VMG (5)

1,263*

419

844

WntT, H-ras mutant (12)

WntT, H-ras wild-type (9)

40

31

9

WntT/p53-/-

WntT (10)

113

43

70

WntT/Pten+/- LOH (3)

WntT (10)

115

45

70

  1. Expression ratio is computed by dividing the average expression level of the A group by the average expression level of the B group. The numbers of differentially expressed genes were determined by random permutation (P < 0.001), as described in the Materials and method section. *In selected comparisons, to reduce potential false signals due to stromal effects, the genes that were less than three-fold different in expression were filtered out from the listed total number of genes. LOH, loss of heterozygosity.