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Table 2 Numbers of genes that are differentially expressed

From: Changes in gene expression during the development of mammary tumors in MMTV-Wnt-1transgenic mice

Comparisons Number of genes differentially expressed
Tissue A (number of samples) Tissue B (number of samples) Total Up Down
WntH (7) VMG (5) 584 121 463
WntT (23) WntH (7) 388* 112 276
WntT (23) NeuT (12) 1,296 624 672
NeuT (12) VMG (5) 1,263* 419 844
WntT, H-ras mutant (12) WntT, H-ras wild-type (9) 40 31 9
WntT/p53-/- WntT (10) 113 43 70
WntT/Pten+/- LOH (3) WntT (10) 115 45 70
  1. Expression ratio is computed by dividing the average expression level of the A group by the average expression level of the B group. The numbers of differentially expressed genes were determined by random permutation (P < 0.001), as described in the Materials and method section. *In selected comparisons, to reduce potential false signals due to stromal effects, the genes that were less than three-fold different in expression were filtered out from the listed total number of genes. LOH, loss of heterozygosity.