A diagrammatic representation of some proteins important for the integration of internal and external signals that control flowering time by influencing the transition from vegetative to flowering growth. The autonomous pathway is independent of environmental cues and depends on an endogenous program of development to regulate flowering. Proteins involved in the responses to photoperiod and circadian signals include PSEUDO-RESPONSE REGULATOR 7 (PRR7), FLAVIN-BINDING, KELCH REPEAT, F-BOX 1 (FKF1), CYCLING DOF FACTOR 1 (CDF1) and CONSTANS (CO). The vernalization pathway is mediated in part by VERNALIZATION INSENSITIVE 3 (VIN3), FRIGIDA (FRI), and FLOWERING LOCUS C (FLC). Ultraviolet (UV) light may act through FIDGET. These inputs appear to be integrated by FLOWERING LOCUS T (FT) and SUPPRESSOR OF OVEREXPRESSION OF CONSTANS 1 (SOC1) that in turn act through APETALA1 (AP1) and LEAFY (LFY) to regulate flowering. See text for details.