Discovery of estrogen receptor α target genes and response elements in breast tumor cells

Table 2 Comparative analysis of predicted EREs in 22 human and mouse orthologous gene pairs

Gene symbol	Human		Mouse		% Identity*		Relative position* (Δd)
	RefSeq ID	Number of predictions	RefSeqID	Number of predictions	Core ERE	Flanking region
ALOX12B	NM_001139	3	NM_009659	4	100	87	40
NRIP1	NM_003489	2	NM_173440	4	100	72	70
GREB1	NM_014668	2	NM_015764	2	100	72	1,720
ACP33	NM_016630	3	NM_138584	4	100	66	46
F10	NM_000504	2	NM_007972	6	90	49	2,003
SERPINE1	NM_000602	4	NM_008871	3	90	23	41
CTSD	NM_001909	3	NM_009983	1	90	26	1,310
OAZIN	NM_015878	1	NM_018745	1	90	19	2,264
PADI3	NM_016233	4	NM_011060	2	90	21	4,153
Unknown	NM_017770	2	NM_019423	1	90	28	3,828
JDP1	NM_021800	1	NM_013888	1	90	30	1,089
NIF3L1	NM_021824	1	NM_022988	2	90	28	955
SCN1B	NM_001037	2	NM_011322	1	80	36	2,716
STC2	NM_003714	1	NM_011491	2	80	26	2,638
LOR	NM_000427	2	NM_008508	2	70	32	4,253
ADCY9	NM_001116	4	NM_009624	1	70	28	3,042
AHCYL1	NM_006621	1	NM_145542	2	70	32	2,190
CISH	NM_013324	1	NM_009895	3	70	19	1,624
HSPC111	NM_016391	1	NM_178605	1	70	19	1,302
FLJ22269	NM_032219	2	NM_172883	1	70	47	3,391
DNAJC1	NM_022365	1	NM_007869	1	60	30	1,672
CDC42EP3	NM_006449	1	NM_026514	1	50	25	451

*The % identity and relative positions of EREs refer to the predicted pairs with the highest conservation between the two organisms.

ISSN: 1474-760X