TY - JOUR AU - Brands, B. AU - Hirst, M. AU - Gowdey, C. W. AU - Baskerville, J. C. PY - 1978 DA - 1978// TI - Analgesia duration and physical dependence in mice after a single injection of three heroin salts and morphine sulphate in various vehicles. JO - Arch Int Pharmacodyn Ther VL - 231 ID - Brands1978 ER - TY - JOUR AU - Kalgutkar, A. S. AU - Zhao, Z. PY - 2001 DA - 2001// TI - Discovery and design of selective cyclooxygenase-2 inhibitors as non-ulcerogenic, anti-inflammatory drugs with potential utility as anti-cancer agents. JO - Curr Drug Targets VL - 2 UR - https://doi.org/10.2174/1389450013348830 DO - 10.2174/1389450013348830 ID - Kalgutkar2001 ER - TY - JOUR AU - Peterson, R. T. AU - Shaw, S. Y. AU - Peterson, T. A. AU - Milan, D. J. AU - Zhong, T. P. AU - Schreiber, S. L. AU - MacRae, C. A. AU - Fishman, M. C. PY - 2004 DA - 2004// TI - Chemical suppression of a genetic mutation in a zebrafish model of aortic coarctation. JO - Nat Biotechnol VL - 22 UR - https://doi.org/10.1038/nbt963 DO - 10.1038/nbt963 ID - Peterson2004 ER - TY - JOUR AU - Gill, M. S. AU - Olsen, A. AU - Sampayo, J. N. AU - Lithgow, G. J. PY - 2003 DA - 2003// TI - An automated high-throughput assay for survival of the nematode Caenorhabditis elegans. JO - Free Radic Biol Med VL - 35 UR - https://doi.org/10.1016/S0891-5849(03)00328-9 DO - 10.1016/S0891-5849(03)00328-9 ID - Gill2003 ER - TY - JOUR AU - Tucker, C. L. AU - Fields, S. PY - 2004 DA - 2004// TI - Quantitative genome-wide analysis of yeast deletion strain sensitivities to oxidative and chemical stress. JO - Comp Funct Genomics VL - 5 UR - https://doi.org/10.1002/cfg.391 DO - 10.1002/cfg.391 ID - Tucker2004 ER - TY - JOUR AU - Baetz, K. AU - McHardy, L. AU - Gable, K. AU - Tarling, T. AU - Reberioux, D. AU - Bryan, J. AU - Andersen, R. J. AU - Dunn, T. AU - Hieter, P. AU - Roberge, M. PY - 2004 DA - 2004// TI - Yeast genome-wide drug-induced haploinsufficiency screen to determine drug mode of action. JO - Proc Natl Acad Sci USA VL - 101 UR - https://doi.org/10.1073/pnas.0307122101 DO - 10.1073/pnas.0307122101 ID - Baetz2004 ER - TY - JOUR AU - Lum, P. Y. AU - Armour, C. D. AU - Stepaniants, S. B. AU - Cavet, G. AU - Wolf, M. K. AU - Butler, J. S. AU - Hinshaw, J. C. AU - Garnier, P. AU - Prestwich, G. D. AU - Leonardson, A. PY - 2004 DA - 2004// TI - Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes. JO - Cell VL - 116 UR - https://doi.org/10.1016/S0092-8674(03)01035-3 DO - 10.1016/S0092-8674(03)01035-3 ID - Lum2004 ER - TY - JOUR AU - Giaever, G. AU - Flaherty, P. AU - Kumm, J. AU - Proctor, M. AU - Nislow, C. AU - Jaramillo, D. F. AU - Chu, A. M. AU - Jordan, M. I. AU - Arkin, A. P. AU - Davis, R. W. PY - 2004 DA - 2004// TI - Chemogenomic profiling: identifying the functional interactions of small molecules in yeast. JO - Proc Natl Acad Sci USA VL - 101 UR - https://doi.org/10.1073/pnas.0307490100 DO - 10.1073/pnas.0307490100 ID - Giaever2004 ER - TY - JOUR AU - Giaever, G. AU - Shoemaker, D. D. AU - Jones, T. W. AU - Liang, H. AU - Winzeler, E. A. AU - Astromoff, A. AU - Davis, R. W. PY - 1999 DA - 1999// TI - Genomic profiling of drug sensitivities via induced haploinsufficiency. JO - Nat Genet VL - 21 UR - https://doi.org/10.1038/6791 DO - 10.1038/6791 ID - Giaever1999 ER - TY - JOUR AU - Uetz, P. AU - Giot, L. AU - Cagney, G. AU - Mansfield, T. A. AU - Judson, R. S. AU - Knight, J. R. AU - Lockshon, D. AU - Narayan, V. AU - Srinivasan, M. AU - Pochart, P. PY - 2000 DA - 2000// TI - A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae. JO - Nature VL - 403 UR - https://doi.org/10.1038/35001009 DO - 10.1038/35001009 ID - Uetz2000 ER - TY - JOUR AU - Tong, A. H. AU - Evangelista, M. AU - Parsons, A. B. AU - Xu, H. AU - Bader, G. D. AU - Page, N. AU - Robinson, M. AU - Raghibizadeh, S. AU - Hogue, C. W. AU - Bussey, H. PY - 2001 DA - 2001// TI - Systematic genetic analysis with ordered arrays of yeast deletion mutants. JO - Science VL - 294 UR - https://doi.org/10.1126/science.1065810 DO - 10.1126/science.1065810 ID - Tong2001 ER - TY - JOUR AU - Shoemaker, D. D. AU - Lashkari, D. A. AU - Morris, D. AU - Mittmann, M. AU - Davis, R. W. PY - 1996 DA - 1996// TI - Quantitative phenotypic analysis of yeast deletion mutants using a highly parallel molecular bar-coding strategy. JO - Nat Genet VL - 14 UR - https://doi.org/10.1038/ng1296-450 DO - 10.1038/ng1296-450 ID - Shoemaker1996 ER - TY - JOUR AU - Winzeler, E. A. AU - Shoemaker, D. D. AU - Astromoff, A. AU - Liang, H. AU - Anderson, K. AU - Andre, B. AU - Bangham, R. AU - Benito, R. AU - Boeke, J. D. AU - Bussey, H. PY - 1999 DA - 1999// TI - Functional characterization of the S. cerevisiaegenome by gene deletion and parallel analysis. JO - Science VL - 285 UR - https://doi.org/10.1126/science.285.5429.901 DO - 10.1126/science.285.5429.901 ID - Winzeler1999 ER - TY - JOUR AU - Weggen, S. AU - Eriksen, J. L. AU - Das, P. AU - Sagi, S. A. AU - Wang, R. AU - Pietrzik, C. U. AU - Findlay, K. A. AU - Smith, T. E. AU - Murphy, M. P. AU - Bulter, T. PY - 2001 DA - 2001// TI - A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity. JO - Nature VL - 414 UR - https://doi.org/10.1038/35102591 DO - 10.1038/35102591 ID - Weggen2001 ER - TY - JOUR AU - Keller, J. J. AU - Giardiello, F. M. PY - 2003 DA - 2003// TI - Chemoprevention strategies using NSAIDs and COX-2 inhibitors. JO - Cancer Biol Ther VL - 2 UR - https://doi.org/10.4161/cbt.214 DO - 10.4161/cbt.214 ID - Keller2003 ER - TY - JOUR AU - Wilkinson, D. S. AU - Pitot, H. C. PY - 1973 DA - 1973// TI - Inhibition of ribosomal ribonucleic acid maturation in Novikoff hepatoma cells by 5-fluorouracil and 5-fluorouridine. JO - J Biol Chem VL - 248 ID - Wilkinson1973 ER - TY - JOUR AU - Mayo, V. S. AU - De Kloet, S. R. PY - 1972 DA - 1972// TI - Effect of 5-fluorouracil on the synthesis and stability of ribosomal RNA in Saccharomyces carlsbergensis. JO - Arch Biochem Biophys VL - 153 UR - https://doi.org/10.1016/0003-9861(72)90369-4 DO - 10.1016/0003-9861(72)90369-4 ID - Mayo1972 ER - TY - JOUR AU - Berger, E. PY - 1977 DA - 1977// TI - The ribosomes of Drosophila. Normal and defective ribosome biosynthesis in Drosophilacell cultures. JO - Mol Gen Genet VL - 155 UR - https://doi.org/10.1007/BF00268558 DO - 10.1007/BF00268558 ID - Berger1977 ER - TY - JOUR AU - Ghoshal, K. AU - Jacob, S. T. PY - 1997 DA - 1997// TI - An alternative molecular mechanism of action of 5-fluorouracil, a potent anticancer drug. JO - Biochem Pharmacol VL - 53 UR - https://doi.org/10.1016/S0006-2952(97)00040-3 DO - 10.1016/S0006-2952(97)00040-3 ID - Ghoshal1997 ER - TY - JOUR AU - Santi, D. V. AU - McHenry, C. S. PY - 1972 DA - 1972// TI - 5-Fluoro-2'-deoxyuridylate: covalent complex with thymidylate synthetase. JO - Proc Natl Acad Sci USA VL - 69 UR - https://doi.org/10.1073/pnas.69.7.1855 DO - 10.1073/pnas.69.7.1855 ID - Santi1972 ER - TY - JOUR AU - Mori, H. PY - 2004 DA - 2004// TI - From the sequence to cell modeling: comprehensive functional genomics in Escherichia coli. JO - J Biochem Mol Biol VL - 37 UR - https://doi.org/10.5483/BMBRep.2004.37.1.083 DO - 10.5483/BMBRep.2004.37.1.083 ID - Mori2004 ER - TY - JOUR AU - Pratt, R. J. AU - Aramayo, R. PY - 2002 DA - 2002// TI - Improving the efficiency of gene replacements in Neurospora crassa: a first step towards a large-scale functional genomics project. JO - Fungal Genet Biol VL - 37 UR - https://doi.org/10.1016/S1087-1845(02)00032-4 DO - 10.1016/S1087-1845(02)00032-4 ID - Pratt2002 ER - TY - JOUR AU - Silva, J. M. AU - Mizuno, H. AU - Brady, A. AU - Lucito, R. AU - Hannon, G. J. PY - 2004 DA - 2004// TI - RNA interference microarrays: high-throughput loss-of-function genetics in mammalian cells. JO - Proc Natl Acad Sci USA VL - 101 UR - https://doi.org/10.1073/pnas.0400165101 DO - 10.1073/pnas.0400165101 ID - Silva2004 ER - TY - JOUR AU - Paddison, P. J. AU - Silva, J. M. AU - Conklin, D. S. AU - Schlabach, M. AU - Li, M. AU - Aruleba, S. AU - Balija, V. AU - O'Shaughnessy, A. AU - Gnoj, L. AU - Scobie, K. PY - 2004 DA - 2004// TI - A resource for large-scale RNA-interference-based screens in mammals. JO - Nature VL - 428 UR - https://doi.org/10.1038/nature02370 DO - 10.1038/nature02370 ID - Paddison2004 ER - TY - JOUR AU - Berns, K. AU - Hijmans, E. M. AU - Mullenders, J. AU - Brummelkamp, T. R. AU - Velds, A. AU - Heimerikx, M. AU - Kerkhoven, R. M. AU - Madiredjo, M. AU - Nijkamp, W. AU - Weigelt, B. PY - 2004 DA - 2004// TI - A large-scale RNAi screen in human cells identifies new components of the p53 pathway. JO - Nature VL - 428 UR - https://doi.org/10.1038/nature02371 DO - 10.1038/nature02371 ID - Berns2004 ER -