Figure 9
The effect of directionality of gene conversion on paralog and ortholog sequence similarity. Sequence similarities represent averages over 1,000 simulations. The effects of different ratios of gene conversion directionality are considered on the sequence similarity of paralogs p1 and d1, and p2 and d2, and of orthologs p1 and p2, and d1 and d2. (a) Conversion proximal to distal 50%, distal to proximal 50%; (b) proximal to distal 25%, distal to proximal 75%; (c) proximal to distal 10%, distal to proximal 90%. Length of simulation 8 × 106 years; generation time 20 years; base substitution rate 4 × 10-8 per nucleotide per generation; gene conversion rate 4 × 10-5 per locus per generation (equivalent to 1.4 × 10-6 per site per generation); mean conversion tract length 352 bp; initial paralog sequence divergence 2%.