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Figure 1 | Genome Biology

Figure 1

From: Chipping away at 'stemness'

Figure 1

Comparison of the numbers of genes found to be enriched in human ES-cell lines in the five studies [1-5]. The circles each represent the number of genes found to be enriched in each cell line; the inner light circles represent genes shared with mouse cell lines (mouse genes not shared with human cell types are omitted. (a) Sperger et al. [1] compared five human ES-cell lines with seminoma and embryonal carcinoma (EC) cells and found 330 genes in common between them all. (b) Sato et al. [2] found 227 genes in common between human and mouse ES cells. (c)Richards et al. [3] found 192 genes that were upregulated in human ES cells compared with other human and mouse SAGE libraries. (d) Abeyta et al. [4] found 76 genes in common between three human ES-cell lines and mouse ES cells. (e) Zeng et al. [5] found 92 genes in common between two human ES-cell lines and mouse ES cells. In (b-d), the inner light circles represent the number of candidate pluripotency genes; in (a), candidate pluripotency genes are those shared by human ES and EC cells but not seminoma cells (565 genes).

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