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Table 2 The bHLH protein structures available in the Protein Data Bank (PDB)

From: An overview of the basic helix-loop-helix proteins

PDB code Protein Chains Protein name Species Group SCOP superfamily CATH homologous superfamily CATH sequence family
1mdy* ABCD MyoD bHLH Mouse A Helix-loop-helix DNA-binding domain MyoD basic-helix-loop-helix domain, subunit B 4.10.280.10.1
1an4 AB USF bHLH Human B Helix-loop-helix DNA-binding domain MyoD basic-helix-loop-helix domain, subunit B 4.10.280.10.2
1an2 AC Max bHLHZ Mouse B Helix-loop-helix DNA-binding domain MyoD basic-helix-loop-helix domain, subunit B 4.10.280.10.2
1hlo AB Max bHLHZ Human B Helix-loop-helix DNA-binding domain MyoD basic-helix-loop-helix domain, subunit B 4.10.280.10.2
1nlw* BE Max bHLHZ Human B Helix-loop-helix DNA-binding domain MyoD basic-helix-loop-helix domain, subunit B 4.10.280.10.2
1nkp* BE Max bHLHZ Human B Helix-loop-helix DNA-binding domain MyoD basic-helix-loop-helix domain, subunit B 4.10.280.10.2
1nkp* AD Myc prot-oncogene bHLHZ Human B Helix-loop-helix DNA-binding domain MyoD basic-helix-loop-helix domain, subunit B 4.10.280.10.2
1am9* ABCD SREBP-1a bHLHZ Human B Helix-loop-helix DNA-binding domain MyoD basic-helix-loop-helix domain, subunit B 4.10.280.10.3
1ukl CDEF SREBP-2 HLHZ Human B NC NC NC
1a0a* AB Pho4 bHLH S. cerevisiae B Helix-loop-helix DNA-binding domain MyoD basic-helix-loop-helix domain, subunit B 4.10.280.10.4
1nlw* AD Mad bHLHZ Human B Helix-loop-helix DNA-binding domain NC NC
  1. The PDB codes and protein names for nine bHLH proteins deposited in the PDB are shown with their superfamily names from the CATH [23] and SCOP [24] classifications and their sequence family numbers from CATH. Max has more than one structure solved, including two complexes (1nkp, Max-Myc and 1nlw, Max-Mad). *Structures shown in Figure 1; NC, the protein is not yet included in the CATH or SCOP protein structure classifications. SREBP, steroid response element binding protein. 'Protein chains' indicates the chain identification letter assigned to individual subunits in the PDB files.
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Genome Biology

ISSN: 1474-760X

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