Figure 2

Demonstration of the power of visualization in transcriptome analyses. The dataset used is from Hamoen and colleagues [24]. The strength of up- or downregulation is depicted by the intensity of the color. Stem-loop structures indicate annotated terminators. (a,b) Probable cases of low-level activation. Genes are colored on the basis of expression ratios from DNA macroarray experiments [24], without applying a stringent cutoff. Red shades indicate ComK-dependent activation, whereas green shows downregulation. Gray shades indicate ratios of around 1. Stem-loop structures are used to depict annotated terminators. K-boxes are shown by vertical red lines. (c,d) Putative cases of transcriptional readthrough. Red shades indicate significant ComK-dependent expression. K-boxes are depicted by vertical green lines. Gray genes are not significantly ComK-dependent. (e,f) Probable cases in which antisense RNA has a role (colors and symbols identical to (c) and (d)).