Table 4 Comparison of candidate gene list generated by multi-species cross-platform analysis with that obtained using a single-experiment analysis

From: Orthologous gene-expression profiling in multi-species models: search for candidate genes

	U133		U95		U74		U34
Gene ID	FC	pV	FC	pV	FC	pV	FC	pV
TCF21	x	x	X		x	x
ADPRH	x	x	X				X
AREG	x	x			X		X
S100A9	x	x			X		X
EST	x	x			X		X
EST	x	x			X
IL-13	x	x					X
GAPD	x	x					X
LGALS3	x	x					X
YWHAZ	x		x	x			X
KCNJ6			x	x	X		X
CXCR4			x	x	X		X
CCL2			x	x	X		X
BHLHB2			x	x	X
GJA-1			x	x
AQP-1			x	x
GADD45A	X				x	x	x	x
MAT2A			X		x	x	x
ADMR					x	x	x	x
CDKN1A			X		x	x
PRKAR2A			X		x	x
GABRD					x	x	X
TNFSF6					x	x	X
F3					x	x	X
IFRD1					x	x	X
GCH1					x	x	X
CEBPD					x	x
NPY1R					x	x
EST		X	X		X		x	x
SLC2A3	X		X				x	x
DNAJA1	X				X		x	x
BAIAP3			X		X		x	x
IL-6			X		X		x	x
PSMB5	X						x	x
GBP2					X		x	x
CYCS					X		x	x
CD2					X		x	x
EIF2S1					X		x	x
CD79B					X		x	x
ENSA					X		x	x
LAT							x	x
RPLP2	X		X				X
ARPC4	X		X				X
NOS1		X	X				X
EGFR			X		X		X
P4HA1			X		X		X
PAI-1			X		X		X
ATF3			X		X		X
RAB5A			X		X		X
IL1R2			X		X		X
BTG1	X				X
HSPA8	X				X
CEBPB	X				X
ARG2		X			X
MYBPH			X		X
COX1			X		X
MST1			X		X
FGA			X				X
ACADL			X				X
TFF2					X		X
PLCG2					X		X
PLAA					X		X
PDHB					X		X
BTG2					X		X
IL-1B					X		X
AIF1					X		X
XCL1					X		X
PLAUR					X
GCLC					X
Other ALI-related genes
SP-C	x	x
ODC-1	X				X		x	x
SP-B	X
ACE							X
SP-D			NA	NA
TGFA							NA	NA
IL-8					NA	NA	NA	NA
TNFA					NA	NA	NA	NA

FC, fold change in gene expression; pV, p-value produced by variance-independent double-tailed t-test of mechanical stretch vs control. X or x denotes changes in gene expression greater than 1.3-fold or p < 0.05; lower-case x represent genes that satisfied both filtering conditions. NA (not available) represents genes that were not present on the array. Rows in bold depict genes presented in Table 2.

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