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Table 4 Comparison of candidate gene list generated by multi-species cross-platform analysis with that obtained using a single-experiment analysis

From: Orthologous gene-expression profiling in multi-species models: search for candidate genes

  U133 U95 U74 U34
Gene ID FC pV FC pV FC pV FC pV
TCF21 x x X   x x   
ADPRH x x X     X  
AREG x x    X   X  
S100A9 x x    X   X  
EST x x    X   X  
EST x x    X    
IL-13 x x      X  
GAPD x x      X  
LGALS3 x x      X  
YWHAZ x   x x    X  
KCNJ6    x x X   X  
CXCR4    x x X   X  
CCL2    x x X   X  
BHLHB2    x x X    
GJA-1    x x     
AQP-1    x x     
GADD45A X     x x x x
MAT2A    X   x x x  
ADMR      x x x x
CDKN1A    X   x x   
PRKAR2A    X   x x   
GABRD      x x X  
TNFSF6      x x X  
F3      x x X  
IFRD1      x x X  
GCH1      x x X  
CEBPD      x x   
NPY1R      x x   
EST   X X   X   x x
SLC2A3 X   X     x x
DNAJA1 X     X   x x
BAIAP3    X   X   x x
IL-6    X   X   x x
PSMB5 X       x x
GBP2      X   x x
CYCS      X   x x
CD2      X   x x
EIF2S1      X   x x
CD79B      X   x x
ENSA      X   x x
LAT        x x
RPLP2 X   X     X  
ARPC4 X   X     X  
NOS1   X X     X  
EGFR    X   X   X  
P4HA1    X   X   X  
PAI-1    X   X   X  
ATF3    X   X   X  
RAB5A    X   X   X  
IL1R2    X   X   X  
BTG1 X     X    
HSPA8 X     X    
CEBPB X     X    
ARG2   X    X    
MYBPH    X   X    
COX1    X   X    
MST1    X   X    
FGA    X     X  
ACADL    X     X  
TFF2      X   X  
PLCG2      X   X  
PLAA      X   X  
PDHB      X   X  
BTG2      X   X  
IL-1B      X   X  
AIF1      X   X  
XCL1      X   X  
PLAUR      X    
GCLC      X    
Other ALI-related genes         
SP-C x x       
ODC-1 X     X   x x
SP-B X        
ACE        X  
SP-D    NA NA     
TGFA        NA NA
IL-8      NA NA NA NA
TNFA      NA NA NA NA
  1. FC, fold change in gene expression; pV, p-value produced by variance-independent double-tailed t-test of mechanical stretch vs control. X or x denotes changes in gene expression greater than 1.3-fold or p < 0.05; lower-case x represent genes that satisfied both filtering conditions. NA (not available) represents genes that were not present on the array. Rows in bold depict genes presented in Table 2.