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Table 3 Genes involved in cell adhesion, lipogenesis and immune cell biology are modulated in white adipose tissue of RTH and iT3 mice

From: Multi-tissue gene-expression analysis in a mouse model of thyroid hormone resistance

 

WAT

Clone ID and UniGene name

iT3

RTH

Cell Communication: cell adhesion

  

484261 : keratin complex 1, acidic, gene 13

NC

2.36↑

335736 : keratin complex 2, basic, gene 6a

NC

2.73↑

464060 : keratin complex 1, acidic, gene 19

NC

3.54↑

420709 : RIKEN cDNA 5730453H04 gene

NC

14.02↑

762299 : CEA-related cell adhesion molecule 1

NC

4.87↑

776133 : cadherin 1

NC

6.20↑

719965 : desmocollin 2

NC

2.79↑

761578 : desmoglein 2

1.49↓

3.30↑

Metabolism: lipogenesis

  

570675 : glycerol-3-phosphate dehydrogenase 1 (soluble)

2.33↓

1.49↓

352146 : ATP citrate lyase

4.17↓

2.94↓

439735 : Mus musculus, Similar to acetyl-coenzyme A carboxylase, clone 5151139

2.13↓

2.38↓

576881 : fatty acid synthase

2.94↓

3.13↓

693560 : ELOVL family member 6, elongation of long chain fatty acids (yeast)

2.38↓

2.22↓

578436 : phosphogluconate dehydrogenase

1.72↓

3.03↓

949810 : hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)

 

2.50↓

Response to external stimuli: immune cell biology

  

620268 : CD53 antigen

2.27↓

2.86↓

621878 : selectin, lymphocyte

1.33↓

2.44↓

618271 : histocompatibility 2, class II antigen A, beta 1

1.30↓

3.02↓

747378 : histocompatibility 2, class II antigen A, alpha

1.43↓

4.55↓

597433 : chemokine (C-X-C motif) ligand 13

1.27↓

2.44↓

637849 : histocompatibility 2, Q region locus 7

NC

2.27↓

748587 : histocompatibility 2, class II antigen E beta

NC

2.70↓

575397 : chemokine (C-C motif) ligand 6

NC

2.13↓

851752 : chemokine (C-C motif) ligand 22

NC

3.02↓

832043 : chemokine (C-C motif) ligand 19

NC

2.78↓

596470 : CD79B antigen

NC

2.94↓

  1. ↑ indicates fold of activation; ↓ indicates fold of repression; NC indicates no changes (< 1.2-fold).