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Table 1 A summary of the families and superfamilies within Gene3D

From: Progress towards mapping the universe of protein folds

Type of family

Proportion of non-singleton domains

Number of superfamilies

Number of close families

Number of folds

Known structure (CATH)

50%

1,277

93,571

759 + 54

Superfolds (all of known structure)

  

71,080

54

Unknown structure (Pfam)

33%

1,832

61,722

3,871

NewFam

17%

 

52,973

 

Total, excluding singletons:

  

208,266

4,684

  1. Data are from [4]; NewFam denotes uncharacterized families. Around 60,000 singletons are excluded from the analysis. See the text for how the number of folds is estimated for the domains of unknown structure.