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Figure 3 | Genome Biology

Figure 3

From: Prediction of Saccharomyces cerevisiae replication origins

Figure 3

Specificity and sensitivity of ranked predictions. The training set was removed from consideration before generation of this figure. (a) Prediction accuracy is depicted visually as a function of rank. Each prediction was plotted in rank order and coded green if it matched a member of the evaluation set of probable origins or black if it did not, and plotted in rank order from left to right. The high concentration of matches in the top predictions is visible as large blocks of green on the left. (b) Specificity, defined as 100% minus the false positive rate, and sensitivity, 100% minus the false negative rate, are plotted for ranked groups of predictions in cumulative increments of 50 for the first 700 predictions and then for the total ranked list of 1,900 predictions. The ORC/MCM set was used for evaluation. Sensitivity gradually increases, and specificity decreases, as predictions of lower rank are included.

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