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Table 1 Genomic organization of the human caveolin genes and properties of their protein products

From: The caveolin proteins

Human gene Chromosomal location Exon Exon size (bp) Intron Intron size (kb) Residues encoded by exon Length of protein (amino acids) Percentage similarity (identity) to human Cav-1 Percentage similarity (identity) to human Cav-2 Expression patterns
Cav-1 7q31.1 1 30 1
2
3
1.47
31.8
1-10
11-65
66-178
178 - 59 (40) Ubiquitous; highest levels in adipocytes, endothelia, smooth muscle cells, and Type I pneumocytes
Cav-2 7q31.1 1
2a
2b
150
188
151
1
2
0.33
5.76
1-50
51-112
113-162
162 58 (38) - Co-expressed with Cav-1
Cav-3 3p25 1
2
114
342
1 ? 1-38
39-151
151 85 (65) 60 (39) Muscle-specific; primarily in skeletal and cardiac myocytes
  1. Abbreviations: bp, base pairs; kb, kilobases; ?, unknown. Modified from Razani et al. [42].