| LexA cell-cycle map* | Gal4 proteome-wide map†| Common |
---|
Interactions | 1,814 | 20,439 | 28 |
Proteins | 488 | 6,951 | 347 |
Proteins as BD fusions | 106 | 3,616 | 46 |
Proteins as AD fusions | 403 | 5,425 | 250 |
Proteins as AD and BD | 21 | 2,090 | 8 |
Degree exponent‡ | 1.72 | 1.91 | NA |
Mean path length§ | 3.3 | 4.1 | NA |
- *The LexA interactions are from this study, listed in Additional data file 3. †The Gal4 interactions are from Giot et al. [6]. The chance of observing more than two common interactions between the Gal4 map and a random network with the same topological properties as the LexA map is < 10-6 (see Materials and methods). ‡The degree exponent and mean path length are topological properties of the networks. The degree exponent is γ in the equation P(k) = k-γ, where k is the degree or number of interactions per protein, and P(k) is the distribution of proteins with k interactions. §The mean path length is the shortest number of links between a pair of proteins, averaged over all pairs in the network.