Probability scores and cluster size. (a) The lowest probability scores determined for clusters containing the following functional group signature genes were identified: AC, actin cytoskeleton; BST, B-cell signal transduction; EGT, ER/Golgi trafficking; ERUPR, ER stress/unfolded protein response; ICS, immunoglobulin class switching; IA, inflammation and adhesion; NFκB, NFκB signaling; OBS, other B-cell signaling; P, proliferation; RNA, RNA maturation and splicing. The mean (open diamond), standard error (green line) and standard deviation (thin black line and bars) of the minimum probability scores for SA, CAST, HC and PAM are shown together with the minimum probability score for the corresponding consensus cluster (red circle). (b) The cluster size (s
) (open circles) and number of defining functional group genes (FG) (open squares) for the NFκB signaling and ER/UPR functional groups are shown together with the FG/s
ratio (open diamonds).