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Table 1 Human genes expressed in the liver with alternative 3' splice site exons (A3Es) or alternative 5' splice site exons (A5Es)

From: Variation in alternative splicing across human tissues

Splicing type Ensembl gene ID Gene name Exon numbers Fold-change above median expression, HG-U95A Fold-change above median expression, MG-U74A
A5E;A3E 091513 Serotransferrin precursor, TF 8, 9; 4 100 100
A5E;A3E 115414 Fibronectin precursor, FN1 36; 31 10 -
A5E;A3E 117601 Antithrombin-III precursor, SERPINC1 5; 4 100 100
A5E;A3E 136872 Fructose-bisphosphate aldolase, ALDOB 3, 8; 4 100 10
A5E;A3E 140833 Haptoglobin-related protein precursor, HPR 3 100 10
A5E;A3E 151790 Tryptophan 2,3-dioxygenase, TDO2 3, 5; 4 10 100
A5E;A3E 171759 Phenylalanine-4-hydroxylase, PAH 6; 4,10 - 100
A5E 047457 Ceruloplasmin precursor, CP 14, 16 3 -
A5E 055957 Inter-alpha-trypsin inhibitor heavy chain H1 precursor, ITIH1 21 100 10
A5E 111275 Aldehyde dehydrogenase, ALDH2 12 3 3
A5E 132386 Pigment epithelium-derived factor precursor, SERPINF1 4 10 10
A5E 138356 Aldehyde oxidase, AOX1 27, 29 3 3
A5E 138413 Isocitrate dehydrogenase, IDH1 3 1 -
A5E 145692 Betaine-homocysteine S-methyltransferase, BHMT 4 10 100
A5E 160868 Cytochrome P450, CYP3A4 5 10 10
A5E 171766 Glycine amidinotransferase, GATM 8 3 3
A3E 080618 Carboxypeptidase, CBP2 10 - -
A3E 080824 Heat shock protein HSP 90-alpha, HSPCA 8 - -
A3E 096087 Glutathione S-transferase, GSTA2 4, 6 10 10
A3E 106927 Protein precursor, AMBP 5, 9 100 100
A3E 110958 Telomerase-binding protein P23, TEBP 5 <1 1
A3E 134240 Hydroxymethylglutaryl-CoA synthase, HMGCS2 8 10 -
A3E 138115 Cytochrome P450, CYP2C8 4 100 10
A3E 145192 Alpha-2-HS-glycoprotein precursor, AHSG 6 100 100
A3E 163631 Serum albumin precursor, ALB 9 100 100
A3E 171557 Fibrinogen gamma chain precursor, FGG 4 100 100
A3E 174156 Glutathione S-transferase, GSTA3 4, 6 10 10
  1. Examples of human AS genes found to exhibit A3E and/or A5E splicing with both isoforms detected in liver-derived ESTs. AS types are listed in the first column, followed by the last six digits of the Ensembl gene number, the gene name and alternative exon numbers. The last two columns list expression levels in human liver and mouse liver tissues, respectively, expressed in terms of the fold-change relative to the median expression level in other tissues (from the DNA microarray data of [43] and [45], respectively).