Table 2 Functional predictions and comparisons with predictions obtained by other means
Protein name | Class | Predicted function (this study) | Prediction after [8] | Prediction after [28] | Prediction after [18] | GO annotations, September 2003 [30] and predictions after [29] |
|---|---|---|---|---|---|---|
FLM1 | 1, 3 | Amino acid metabolism, cell cycle control (0) | ≈ (0) | ≠ (0) | Mitochondrion organization and biogenesis | |
VTS1 | 4 | Cell cycle control (0) | ≈ (0) | Protein-vacuolar targeting | ||
YPR171W | 7 | Cell polarity (1) | ≈ (1) | Cell polarity and structure, actin cytoskeleton organization and biogenesis | ||
YBR108W | 7 | Cell polarity | ≈ | Unknown | ||
YGR268C | 7, 55 | Cell polarity, cell structure, vesicular transport | ≈ | Unknown | ||
DSE1 | 8, 25 | Cell polarity, mating response (1) | Cell wall organization and biogenesis | |||
YKL082C | 8 | Cell polarity | ≈ | Unknown | ||
YMR322C | 10 | Cell stress, other metabolism | ≈ | ≈ | Unknown | |
VPS64 | 14, 60 | Cell structure, protein folding (1) | ≠ (1) | Protein-vacuolar targeting, cell cycle arrest in response to pheromone | ||
YFR008W | 14, 60 | Cell structure, protein folding (0) | ≠ (1) | Cell cycle arrest in response to pheromone | ||
YNL127W | 14, 60 | Cell structure, protein folding (0) | ≈ (1) | Cell cycle arrest in response to pheromone | ||
YJL019W | 22 | DNA synthesis (1) | ≈ (1) | ≈ (1) | Spindle pole duplication | |
PST2 | 24, 54 | Mating response, differentiation, signal transduction | ≠ | ≈ | Unknown | |
YLL049W | 29 | Mitosis | ≠ | Unknown | ||
YNR069C | 29 | Mitosis | Unknown | |||
NIS1 | 30 | Nucleus-cytoplasm transport (0) | ≠ (0) | Regulation of mitosis | ||
YKL061W | 30 | Nucleus-cytoplasm transport | ≠ | Unknown | ||
YDR489W | 30 | Nucleus-cytoplasm transport (0) | ≠ (0) | DNA-dependent DNA replication | ||
YHL018W | 33 | PolI transcription | Unknown | |||
YDR179C | 35 | PolII transcription (1) | ≠ (0) | Protein synthesis turnover, protein deneddylation | ||
YMR025W | 35 | PolII transcription (1) | ≠ (0) | Protein synthesis turnover, protein deneddylation | ||
YJL058C | 36 | PolII transcription | ≠ | Unknown | ||
SOH1 | 37 | PolII transcription (1) | Transcription from polII promoter, DNA repair | |||
YJR083C | 37 | PolII transcription | ≈ | Unknown | ||
YGL230C | 38 | PolII transcription | ≠ | Unknown | ||
VAC14 | 43 | Protein degradation (0) | ≠ (0) | Intermediate and energy metabolism, transcription, DNA maintenance, chromatin structure, phospholipid metabolism, vacuole inheritance | ||
AKL1 | 43 | Protein degradation | ≠ | Unknown | ||
YHR115C | 43 | Protein degradation | ≠ | Unknown | ||
YPL105C | 48 | Protein synthesis | ≠ | Unknown | ||
YLR424W | 49 | RNA processing and modification | ≈ | Unknown | ||
YKR022C | 49 | RNA processing and modification | ≈ | Unknown | ||
AIR2 | 52 | RNA processing and modification (1) | RNA metabolism, mRNA nucleus export | |||
DHH1 | 52 | RNA processing and modification (1) | Deadenylation-dependent decapping, NOT mRNA catabolism, nonsense mediated | |||
YEL015W | 52 | RNA processing and modification (1) | ≈ (1) | = (1) | ≠ (0) | RNA metabolism |
YOR285W | 54 | Signal transduction | ≠ | Unknown | ||
YGL161C | 56 | Vesicular transport | ≈ | ≈ | Unknown | |
YDR100W | 56 | Vesicular transport | ≈ | ≈ | Unknown | |
YDR425W | 56 | Vesicular transport (1) | Protein, transport | |||
YDR084C | 56 | Vesicular transport | ≈ | Unknown | ||
YGL198W | 56 | Vesicular transport | ≈ | Unknown | ||
YPL246C | 56 | Vesicular transport | ≈ | Unknown | ||
YLR285W | 57 | Vesicular transport (0) | ≠ (0) | Chromatin silencing at ribosomal DNA, nicotinamide metabolism |