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Figure 1 | Genome Biology

Figure 1

From: Functional classification of proteins for the prediction of cellular function from a protein-protein interaction network

Figure 1

Flowchart of PRODISTIN. (a) A graph is constructed from a list of binary protein-protein interactions. (b) A functional distance based on the identity of the shared interactors is calculated among all proteins. (c) The distance matrix obtained is used to build a classification tree, on which functional classes are subsequently determined and analyzed by evaluating (d) their statistical robustness and (e) their biological relevance.

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Genome Biology

ISSN: 1474-760X

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