| |
GO molecular function class
|
|---|
| |
Transcription regulator
|
Apoptosis regulator
|
Cell adhesion molecule
|
Binding
|
Enzyme
|
Transporter
|
Signal transducer
|
Translation regulator
|
Motor
|
Enzyme regulator
|
Structural molecule
|
Chaperone
|
|---|
|
Actual miRNAs
|
113
|
6
|
10
|
146
|
128
|
35
|
66
|
4
|
6
|
9
|
6
|
1
|
|
Random miRNAs (average)
|
43
|
1
|
2
|
98
|
88
|
22
|
41
|
2
|
4
|
9
|
7
|
1
|
|
Standard deviation
|
± 7.5
|
± 0.9
|
± 1.5
|
± 13.3
|
± 13.7
|
± 4.9
|
± 9.7
|
± 1.3
|
± 2.2
|
± 3.9
|
± 2.6
|
± 1.2
|
|
Z-score
|
9.3
|
5.9
|
5.0
|
3.6
|
2.9
|
2.7
|
2.6
|
1.4
|
1.0
|
0.01
|
-0.3
|
-0.3
|
- Integers are number of detected conserved cases in each class. The standard deviation is for 50 experiments. The Z-scores for seven functional classes indicate over-represention for actual miRNA target genes. The thresholds used are S: 100; ΔG: -19 kcal/mol; ID: 70%.
