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Figure 3 | Genome Biology

Figure 3

From: Evolution of mosaic operons by horizontal gene transfer and gene displacement in situ

Figure 3

Genes with different phylogenetic affinities in the lipid biosynthesis operon of Rickettsia. (a) Organization of the lipid biosynthesis operon and surrounding genes in Rickettsia prowazekii and Rickettsia conorrii (operons from three other alpha-proteobacteria are shown for comparison). COG0020 - undecaprenyl pyrophosphate synthase, UppS; COG0575 - CDP-diglyceride synthetase; COG0750 - predicted membrane-associated Zn-dependent proteases; COG0233 - ribosome recycling factor; COG0528 - uridylate kinase; COG0745 - OmpR-like response regulator; COG0642 - signal transduction histidine kinase; COG0729 - outer membrane protein; COG2919 - septum formation initiator; COG0743 - 1-deoxy-D-xylulose 5-phosphate reductoisomerase. The designations are as in Figure 1a. For species abbreviations, see Materials and methods. (b,c) Unrooted maximum-likelihood tree for UppS (b) and CdsA (c); the designations are as in Figure 1b.

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