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Table 4 Protein domain enrichment found in recently duplicated mouse genes*

From: Recent segmental and gene duplications in the mouse genome

InterPro entry ID

Protein domain description

Number found in 608 duplicated genes

Number found in all 16,515 annotated genes in genome

Enrichment†

IPR000276

Rhodopsin-like GPCR superfamily

135

1229

3.0

IPR000725

Olfactory receptor

103

861

3.3

IPR003006

Immunoglobulin/major histocompatibility complex

46

372

3.4

IPR004072

Vomeronasal receptor, type 1

31

108

7.8

IPR001909

KRAB box

23

103

6.1

IPR001254

Serine protease, trypsin family

21

117

4.9

IPR002401

E-class P450, group I

20

61

8.9

IPR001128

Cytochrome P450

20

68

8.0

IPR007086

Zn-finger, C2H2 subtype

20

139

3.9

IPR001314

Chymotrypsin serine protease, family S1

19

108

4.8

IPR002403

E-class P450, group IV

17

56

8.2

IPR002397

B-class P450

13

29

11.9

IPR001304

C-type lectin

13

96

3.7

IPR000215

Serpin

12

48

6.8

IPR002402

E-class P450, group II

9

14

18.5

IPR006046

Glycoside hydrolase family 13

7

8

23.0

IPR006047

Alpha amylase, catalytic domain

7

10

19.2

IPR001400

Somatotropin hormone

7

32

6.1

IPR006048

Alpha amylase, C-terminal all-beta domain

6

7

24.7

IPR002018

Carboxylesterase, type B

6

13

12.3

IPR004073

Vomeronasal receptor, type 2

6

13

12.3

IPR001039

Major histocompatibility complex protein, class I

6

17

9.9

IPR001828

Extracellular ligand-binding receptor

6

29

5.5

IPR002213

UDP-glucoronosyl/UDP-glucosyl transferase

5

12

11.8

IPR002448

Odour-binding protein

4

9

13.2

IPR000068

Extracellular calcium-sensing receptor

4

10

11.0

  1. *Only Ensembl gene annotation (608 genes) was used in this analysis. †All results shown are statistically significant with p-values < 10-5 (chi2 test).