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Table 1 Chromosomal regions implicated in panic disorder, phobias and anxiety traits

From: Untangling genetic networks of panic, phobia, fear and anxiety

Phenotype 1q 3q 4q21 4q34 7p 8q 9q 10q 11p 12q 13q 14p 22q Reference
Panic disorder (PD) +++ +    + ++ ++++    + ++++ + ++++ [13, 15, 16, 19]
  + +   + ++      ++*     [11, 17]
  ++          ++     [15, 16]
Agoraphobia (AG) - ++ +       ++      [13]
   ++++*             [13]
PD + AG          +    +   [13]
Specific Phobia + ++   +   ++   + +    +++   [14]
   +++*             [14]
PD + anxiety +   +     ++ ++   +     [17, 19]
Neuroticism ++++    ++++ ++++      ++++ ++++    [12]
Mouse QTL ++++          ++++   ++++ +++ [17, 27]
  1. *One family. Human equivalents of mouse QTLs. The number of + signs indicates the approximate relative significance of the linkage.