Table 1 Top 30 genes showing higher expression in xenograft tumors over cultures for each cell line ranked by fold change

Higher in U118 tumors over cultures (p < 0.01, fold change > 5)

V00594_s_at

MT2A

Metallothionein 2a

M33552_at

LSP1

Lymphocyte-specific protein 1

U41518_at

AQP1

Aquaporin 1 (channel-forming integral protein, 28 kD)

Z24680_at

GARP

Glycoprotein A repetitions predominant

J04599_at

BGN

Biglycan

J03278_at

PDGFRB

Platelet-derived growth factor receptor, beta polypeptide

M11718_at

COL5A2

Collagen, type V, alpha 2

L08096_s_at

TNFSF7

Tumor necrosis factor (ligand) superfamily, member 7

D87002_cds2_at

POM121L1

Similar to rat integral membrane glycoprotein POM121

HG2994-HT4850_s_at

ELN

Elastin (supravalvular aortic stenosis, Williams-Beuren syndrome)

Z74615_at

COL1A1

Collagen, type I, alpha 1

M57399_at

PTN

Pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1)

L07807_s_at

DNM1

Dynamin 1

Z74616_s_at

COL1A2

Collagen, type I, alpha 2

L38486_at

MFAP4

Microfibrillar-associated protein 4

X14885_rna1_s_at

TGFB3

Transforming growth factor, beta 3

U24488_s_at

TNXB

Tenascin XB

D86479_at

AEBP1

AE-binding protein 1

M80563_at

S100A4

S100 calcium-binding protein A4

M18533_at

DMD

Dystrophin (muscular dystrophy, Duchenne and Becker types

HG945-HT945_s_at

ZNF9

Zinc finger protein 9 (a cellular retroviral nucleic acid binding protein)

M93221_at

MRC1

Mannose receptor, C type 1

D12485_at

ENPP1

Ectonucleotide pyrophosphatase/phosphodiesterase 1

HG1078-HT1078_at

FLJ10254

Hypothetical protein FLJ10254

HG2810-HT2921_at

HOXA10

Homeo box A10

M24351_cds3_s_at

PTHLH

Parathyroid hormone-like hormone

D13666_s_at

OSF-2

Osteoblast specific factor 2 (fasciclin I-like)

Z37976_at

LTBP2

Latent transforming growth factor beta binding protein 2

M35878_at

IGFBP3

Insulin-like growth factor binding protein 3

X04412_at

GSN

Gelsolin (amyloidosis, Finnish type)

Higher in A549 tumors over cultures (p < 0.01, fold change > 10)

Z19574_rna1_at

KRT17

Keratin 17

M29540_at

CEACAM5

Carcinoembryonic antigen-related cell adhesion molecule 5

M35252_at

TM4SF3

Transmembrane 4 superfamily member 3

HG371-HT26388_s_at

MUC1

Mucin 1, transmembrane

X52003_at

TFF1

Trefoil factor 1 (breast cancer, estrogen-inducible sequence expressed in)

U40434_at

MSLN

Mesothelin

Z48314_s_at

MUC5AC

Mucin 5, subtypes A and C, tracheobronchial/gastric

M57730_at

EFNA1

Ephrin-A1

L24203_at

TRIM29

Tripartite motif-containing 29

U17760_rna1_at

LAMB3

Laminin, beta 3 (nicein (125 kD), kalinin (140 kD), BM600 (125 kD))

U04313_at

SERPINB5

Serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5

J05068_at

TCN1

Transcobalamin I (vitamin B12 binding protein, R binder family)

AB006781_s_at

LGALS4

Lectin, galactoside-binding, soluble, 4 (galectin 4)

K01396_at

SERPINA1

Serine (or cysteine) proteinase inhibitor, clade A), member 1

M27436_s_at

F3

Coagulation factor III (thromboplastin, tissue factor)

V01512_rna1_at

FOS

v-Fos FBJ murine osteosarcoma viral oncogene homolog

M18728_at

CEACAM6

Carcinoembryonic antigen-related cell adhesion molecule 6

HG2981-HT3127_s_at

CD44

CD44 antigen (homing function and Indian blood group system)

U37283_at

MAGP2

Microfibril-associated glycoprotein-2

U78551_at

MUC5B

Mucin 5, subtype B, tracheobronchial

S77410_at

AGTR1

Angiotensin receptor 1

J04469_at

CKMT1

Creatine kinase, mitochondrial 1 (ubiquitous)

S73591_at

TXNIP

Thioredoxin interacting protein

Y00318_at

IF

I factor (complement)

M35878_at

IGFBP3

Insulin-like growth factor binding protein 3

M34309_at

ERBB3

v-Erb-b2 avian erythroblastic leukemia viral oncogene homolog 3

M95787_at

TAGLN

Transgelin

L34155_at

LAMA3

Laminin, alpha 3 (nicein (150 kD), kalinin (165 kD), BM600 (150 kD), epilegrin)

U65932_at

ECM1

Extracellular matrix protein 1

D87953_at

NDRG1

N-Myc downstream regulated