Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii

Table 3 Size comparison of proposed fused ORF in S. cerevisiae with A. gossypii homolog

S. cerevisiae ORF1			S. cerevisiae ORF2			Fused ORF		A. gossypii		Supporting evidence
Systematic name	Common name	Size (amino acids)	Systematic name	Common name	Size (amino acids)	Size (amino acids)	Reason*	Name	Size (amino acids)
YAR044W		859	YAR042W		256	1,188	FS	AER225W	1,300	Resequenced
YBR074W		103	YBR075W		460	976	2FS	AGL209W	1,012	Resequenced
YBR098W	MMS4	108	YBR100W		112	691	FS	ADL318C	715
YCL001W-A^†		84	YCL001W-B		153	313	2FS	AAL001W	386
YDR474C^†		155	YDR475C	JIP4	555	876	2FS	AEL233C	794
YER039C^†	HVG1	249	YER039C-A		72	341	PS	AFR236C	330	Pseudogene [22]
YFL007W^†	BLM3	1,804	YFL006W		254	2,143	FS	AGL022W	2,146	[46]
YGL046W		262	YGL045W		229	540	3FS	AFR108W	549
YGR272C		152	YGR271C-A^‡		63	233	FS	ABR143C	214
YJL012C	VTC4	648	YJL012C-A^‡		65	721	FS	AGR316C	714	Resequenced
YJL017W		325	YJL016W		171	561	FS	AGR313W	471	Resequenced
YJL019W	MPS3	620	YJL018W		102	682	FS	AGR312W	617	Resequenced
YJL020C	BBC1	446	YJL021C		710	1,156	FS	AGR306C	924	Resequenced
YJL108C^†	PRM10	383	YJL107C		387	770	FS	AFR075C	741	Resequenced
YKL199C^†	YKT9	279	YKL198C	PTK1	399	649	FS	AFR372W	775	Resequenced
YKR103W		1,218	YKR104W		306	1,558	PS	NB^§	NB^§
YLL017W^†	SDC25		YLL016W	SDC25		1,252	FS	ADL038W	1,510	Pseudogene (SGD)
YLL052C^†	AQY2	149	YLL053C		152	286	FS	AGL266C	451
YML002W		737	YML003W		290	1,090	FS	ACR006C	1,072
YMR084W^†		262	YMR085W		432	719	FS	ABL036C	707
YOL163W^†	169	YOL162W			215	553	PS	ACL203C	538	Pseudogene [22]
YPR090W	736	YPR089W			155	888	FS	ABR111C	790	Resequenced

*PS, premature STOP codon; FS, frameshift. ^†Agreement with proposal of Blandin et al. [17] and Wood et al. [18]. ^‡Novel ORFs identified by Blandin et al. [17]. ^§No homolog was found in A. gossypii but YKR103W/YKR104W is a member of a gene family including YLL048C and YHL035C for which A. gossypii homologs were found.

ISSN: 1474-760X