Table 1 Number of genes correlated with tissue metrics at three levels ofconfidence ranked by the number of significant correlations for alpha = 0.01
From: Combined histomorphometric and gene-expression profiling applied to toxicology
Rank | Tissue metric | Confidence level | ||
|---|---|---|---|---|
| Â | Â | 0.05 | 0.01 | 0.001 |
1 | % Clear space (non-stained tissue and cellular elements) | 241 | 74 | 10 |
2 | Area % vacuoles | 155 | 36 | 1 |
3 | Vacuoles/mm2 | 167 | 28 | 1 |
4 | % H&E stained elements | 106 | 19 | 0 |
5 | Area % sinusoids | 74 | 10 | 0 |
6 | Area % other nuclei | 51 | 7 | 0 |
7 | Hepatocyte nuclei/mm2 | 44 | 7 | 1 |
8 | Other nuclei/mm2 | 46 | 5 | 0 |
9 | Total nuclei/mm2 | 39 | 4 | 1 |
10 | Area % hepatocyte nuclei | 55 | 2 | 0 |
11 | Cytoplasmic texture | 19 | 2 | 0 |
Expected false positives | 52 | 10 | 1 | |
Number determined significant | 997 | 194 | 14 | |