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Table 1 Results of comparisons between the second exons of human and baboon genes demonstrating positive selection

From: Duplication and selection in the evolution of primate β-defensin genes

  DEFB1 vs DEFB104 DEFB103 vs DEFB107
  Homo sapiens P. cynocephalus anubis H. sapiens P. cynocephalus anubis
S* 17.917±1.180 17.167±1.169 16.917±1.165 16.833±1.124
N 48.083±1.144 48.833±1.181 49.083±1.156 49.167±1.124
s 6.25±1.954 6.25±1.954 4.5±1.796 4±1.767
n 35.75±3.482 34.75±3.559 27.5±3.382 27±3.373
dS 0.349±0.103 0.364±0.106 0.266±0.104 0.238±0.105
dN 0.744±0.062 0.712±0.063 0.560±0.064 0.549±0.067
Z-test 0.001 0.005 0.020 0.008
Fisher's 0.012 0.019 0.060 0.023
Charge§     
p C 0.498±0.088 0.535±0.102 0.447±0.094 0.409±0.094
p R 0.784±0.077 0.830±0.086 0.571±0.087 0.575±0.085
pR/pC 1.57 1.55 1.28 1.41
M-Y#     
p C 0.577±0.116 0.708±0.108 0.598±0.124 0.581±0.124
p R 0.618±0.092 0.634±0.100 0.467±0.080 0.446±0.082
pR/pC 1.0 0.90 0.78 0.77
  1. *Estimates (6SE) of the number of synonymous sites (S), number of nonsynonymous sites, numbers of synonymous substitutions (s), numbers of nonsynonymous substitutions (n), the number of synonymous substitutions per synonymous site (dS) and the number of nonsynonymous substitutions per nonsynonymous site (dN). The result of a two-tailed Z-test of dN - dS = 0. The result of a Fisher's exact test. §Rates of radical (pR) and conservative (pC) changes in amino-acid properties, with the ratio of radical to conservative changes (pR/pC) for residues categorized in terms of their charges. pR is significantly greater than pC. #Rates of radical (pR) and conservative (pC) changes in amino-acid properties, with the ratio of radical to conservative changes (pR/pC) for residues categorized in terms of the Miyata-Yasunaga classification (M-Y; a combination of polarity and volume).