Skip to main content

Table 1 Results of comparisons between the second exons of human and baboon genes demonstrating positive selection

From: Duplication and selection in the evolution of primate β-defensin genes

 

DEFB1 vs DEFB104

DEFB103 vs DEFB107

 

Homo sapiens

P. cynocephalus anubis

H. sapiens

P. cynocephalus anubis

S*

17.917±1.180

17.167±1.169

16.917±1.165

16.833±1.124

N

48.083±1.144

48.833±1.181

49.083±1.156

49.167±1.124

s

6.25±1.954

6.25±1.954

4.5±1.796

4±1.767

n

35.75±3.482

34.75±3.559

27.5±3.382

27±3.373

dS

0.349±0.103

0.364±0.106

0.266±0.104

0.238±0.105

dN

0.744±0.062

0.712±0.063

0.560±0.064

0.549±0.067

Z-test

0.001

0.005

0.020

0.008

Fisher's

0.012

0.019

0.060

0.023

Charge§

    

p C

0.498±0.088

0.535±0.102

0.447±0.094

0.409±0.094

p R

0.784±0.077

0.830±0.086

0.571±0.087

0.575±0.085

pR/pC

1.57

1.55

1.28

1.41

M-Y#

    

p C

0.577±0.116

0.708±0.108

0.598±0.124

0.581±0.124

p R

0.618±0.092

0.634±0.100

0.467±0.080

0.446±0.082

pR/pC

1.0

0.90

0.78

0.77

  1. *Estimates (6SE) of the number of synonymous sites (S), number of nonsynonymous sites, numbers of synonymous substitutions (s), numbers of nonsynonymous substitutions (n), the number of synonymous substitutions per synonymous site (dS) and the number of nonsynonymous substitutions per nonsynonymous site (dN). The result of a two-tailed Z-test of dN - dS = 0. The result of a Fisher's exact test. §Rates of radical (pR) and conservative (pC) changes in amino-acid properties, with the ratio of radical to conservative changes (pR/pC) for residues categorized in terms of their charges. pR is significantly greater than pC. #Rates of radical (pR) and conservative (pC) changes in amino-acid properties, with the ratio of radical to conservative changes (pR/pC) for residues categorized in terms of the Miyata-Yasunaga classification (M-Y; a combination of polarity and volume).