Extreme conservation of non-repetitive non-coding regions near HoxDcomplex of vertebrates

Table 1 Conservation of sequences in the regions CR-1, 2 and 3 in different vertebrate species

Comparison	CR-1		CR-2		CR-3
	Core	Extended	Core	Extended	Core	Extended
human/included in baboon CR-2	317 [99]	3119 [95]	800 [99.4]	4400 [95]	256	[99.6]
human/rat	317 [98.4]	837 [91]	800 [97.8]	1127 [95]	256 [99.2]	748 [94]
human/mouse	317 [98.4]	846 [92]	800 [97.8]	568 [98]	256 [99.6]	652 [97]
				556 [93]
mouse/rat	317 [98.7]	2180 [95]	800 [98]	1879 [92]	256 [99.6]	855 [81]
		459 [94]		964 [94]		483 [90]
		534 [90]
human/shark	317 [90.2]	253 [88]	800 [93]	581 [92]	256 [93]	414 [90]
		137 [85]		175 [88]
vertebrate	43, 30 [100]		144, 94, 59,		91, 62, 35,
	197 [93]		53, 46 [100]		62 [100]
			463 [96]

Vertebrate conservation is based on human, mouse and shark comparison. Although we find genomic sequences of other vertebrates (fugu and zebrafish) that show conservation in this region, those sequences are in draft form and, therefore, have been excluded from this comparison. Length of core and extended regions of conservation are given in base pairs. Number with in the bracket indicates percent homology.

ISSN: 1474-760X