The rhomboids: a nearly ubiquitous family of intramembrane serine proteases that probably evolved by multiple ancient horizontal gene transfers

Table 2 Statistical comparisons of the best neighbor-joining tree with the hypothesis 1 and hypothesis 2 trees

Kishino-Hasegawa test
Tree	Length	Length difference	SD (difference)	t	p*
Best	4951	-
Hypothesis 1	4966	15	11.9	1.26	0.211
Hypothesis 2	4974	23	10.8	2.12	0.036
Templeton (Wilcoxon signed-ranks) test
Tree	Length	Rank sums	N	z	p*
Best	4951	-
Hypothesis 1	4966	1418.0	69	-1.33	0.185
		-997.0
Hypothesis 2	4974	1244.5	62	-1.97	0.048
		-708.5
Winning-sites (sign) test
Tree	Length	Counts	p*
Best	4951
Hypothesis 1	4966	36	0.810
		-33
Hypothesis 2	4974	40	0.031
		-22

*Probability of getting a more extreme test statistic under the null hypothesis of no difference between the two trees (two-tailed test).

ISSN: 1474-760X