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Table 2 Mating-specific S. cerevisiae genes with orthologs in C. glabrata

From: Evidence from comparative genomics for a complete sexual cycle in the 'asexual' pathogenic yeast Candida glabrata

Gene

Function

MFALPHA2

Mating pheromone α-factor

STE13

Peptidase, α-factor processing

STE6

Exporter of a-factor

FIG4

Lipid phosphatase, pheromone induced

FAR1

Inhibitor of Cdc28-Cln1/2 kinase complexes

CDC24

GTP-GDP exchange factor for Cdc42

SGV1

Kinase, pheromone adaptation

AKR1

Negative regulator in the pheromone response pathway

FUS3

Kinase, activates Ste12 and Far1

KAR5

Required for nuclear membrane fusion during karyogamy

LSG1

Required for normal morphology, mating and sporulation

OPY2

Overproduction causes insensitivity to α-factor arrest

SAG1

α-Agglutinin