Skip to main content

Table 1 The septin genes and proteins in five representative organisms

From: The septins

Species Approved gene name Chromosomal location* Size (amino acids) Mass (kDa) Isoelectric point (pI) Charge Number of predicted coiled coils Accession number
Saccharomyces cerevisiae Cdc3 XII:764137 520 60.0 5.3 A 2 L16548
  Cdc10 III:118342 322 37.0 5.6 A 0 L16549
  Cdc11 X:576294 415 47.6 4.8 A 1 L16550
  Cdc12 VIII:328038 407 46.7 8.2 B 1 L16551
  Spr3 VII:607564 512 59.8 7.3 N 3 U24129
  Spr28 IV:905043 423 48.2 5.8 A 1 NP_010504
  Shs1/Sep7 IV:52446 551 62.6 5.3 A 2 Z74273
Schizosaccharomyces pombe spn1 I:1067997 469 53.7 5.3 A 1 U31742
  spn2 I:960487 331 38.1 8.0 B 0 U29888
  spn3 II:2682372 412 46.6 4.7 A 1 U29889
  spn4 I:1962024 380 44.7 7.0 N 1 U29890
  spn5 I:3044705 464 53.1 8.2 B 1 U29891
  spn6 III:421493 380 44.0 6.9 N 1 AL032824
  spn7 II:161221 428 49.2 5.2 A 0 AF417166
Caenorhabditis elegans unc-59 I:21.15 459 52.9 8.9 B 1 NM_060987
  unc-61 V:6.66 530 60.7 8.9 B 1 NM_182356
Drosophila melanogaster Pnut 44C2 539 60.2 9.0 B 1 NM_165597
  Sep1 19F5 361 41.1 6.1 A 2 NM_167747
  Sep2 92F2 419 48.5 7.4 N 1 NM_079693
  Sep4 15A1 427 49.0 6.9 N 2 NM_167530
  Sep5 43F8 422 48.5 7.3 N 1 NM_165578
Homo sapiens Sept1 16p11.1 366 41.8 5.5 A 2 NM_052838
  Sept2 2q37.3 361 41.5 6.2 A 2 NM_004404
  Sept3 22q13.2 345 39.3 6.8 N 0 NM_145733
  Sept4 17q23 478 55.1 5.7 A 2 NM_004574
  Sept5 22q11.2 369 42.3 6.4 A 2 NM_002688
  Sept6 Xq24 427 48.9 6.4 A 1 NM_145799
  Sept7 7q36.1 418 48.8 9.0 B 1 NM_001788
  Sept8 5q31 483 55.8 5.9 A 1 XM_034872
  Sept9 17q25.3 586 65.4 9.3 B 0 AF189713
  Sept10 8q11.23 517 60.0 6.6 N 1 BC020502
  Sept11 4q21.22 429 49.4 6.4 A 1 NM_018243
  Sept12 16p13.3 358 40.8 6.7 N 0 NM_144605
  1. The data refer to the largest gene products for each gene, deduced from cDNAs on the sequence databases. *The numbers given for the yeast genes refer to the position of the gene along the sequence of the chromosome. A, acidic (pI < 6.5); B, basic (pI > 7.5); N, neutral. The algorithm COILS [56, 57] was used to predict coiled coils, and the peaks above an arbitrary threshold (p > 0.8 at a window size of 14) were counted. The mouse genome has counterparts to each of the 12 human septin genes (not shown). For comparative nomenclature of the mouse and human Sept1-Sept10 genes and the products, see [58].