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Table 3 Ocular gene distribution in mouse and human chromosomes

From: Annotation and analysis of 10,000 expressed sequence tags from developing mouse eye and adult retina

    

Human ortholog of mouse ocular genes

 

Mouse genes

Observed

Expected

Chi-square

Chromosome

M15E

M2PN

MRA

M15E

M2PN

MRA

M15E

M2PN

MRA

M15E

M2PN

MRA

1

47

49

29

53

52

26

64.2

60.7

32.7

1.95

1.24

1.38

2

61

71

29

51

51

19

46.5

44.0

23.7

0.43

1.12

0.94

3

44

39

23

36

31

16

41.5

39.3

21.2

0.74

1.74

1.26

4

61

36

21

20

19

12

30.5

28.8

15.5

3.60

3.33

0.80

5

46

35

21

27

36

7

31.5

29.8

16.1

0.65

1.30

5.11

6

36

38

19

23

28

33

39.0

36.9

19.9

6.58

2.14

8.64

7

66

61

26

27

28

6

32.9

31.1

16.8

1.05

0.30

6.90

8

40

36

21

20

25

15

24.9

23.5

12.7

0.95

0.10

0.43

9

39

48

23

25

19

10

25.7

24.3

13.1

0.02

1.16

0.74

10

39

41

30

19

19

4

28.3

26.7

14.4

3.04

2.23

7.52

11

85

62

42

44

35

19

36.2

34.2

18.4

1.69

0.02

0.02

12

24

16

14

33

35

21

32.7

30.9

16.7

0.00

0.55

1.14

13

21

29

12

14

10

5

14.5

13.7

7.4

0.02

1.00

0.77

14

24

33

16

22

22

18

21.6

20.4

11.0

0.01

0.13

4.46

15

28

28

23

24

23

15

21.2

20.0

10.8

0.37

0.44

1.63

16

20

16

14

31

16

7

17.5

16.5

8.9

10.40

0.02

0.41

17

41

31

25

48

34

25

26.0

24.6

13.3

18.51

3.58

10.36

18

16

14

3

3

7

2

10.8

10.2

5.5

5.61

1.00

2.22

19

33

26

18

25

28

18

23.0

21.7

11.7

0.18

1.82

3.38

20

NA

NA

NA

18

19

7

15.6

14.8

8.0

0.36

1.22

0.12

21

NA

NA

NA

13

7

5

6.3

5.9

3.2

7.14

0.19

1.00

22

NA

NA

NA

21

15

9

11.6

11.0

5.9

7.52

1.45

1.58

X

27

30

18

23

27

17

18.0

17.0

9.2

1.38

5.84

6.65

Total

798

739

427

620

586

316

620

586

316

72.20

31.90

67.46

  1. Chi-square tests with 1 degree of freedom (df = 1) for each chromosome and with df = 22 for the totals were applied to compare the observed distribution of ocular genes with expected distribution calculated based on Human Gene Map. Significant Chi-square values with p < 0.002 are indicated in bold. Marginally significant Chi-square values with p < 0.1 are underscored, if genes from all three libraries showed the same trend of higher or lower density.