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Table 1 MAPPFinder analysis

From: Time- and exercise-dependent gene regulation in human skeletal muscle

Upregulated process   C M T Z Downregulated process C M T Z
6 hours after RE Circadian rhythm 4 10 13 7.2 Oxygen transport 3 8 17 4.5
  Nucleic acid metabolism 59 1570 2905 2.7 Calcium ion transport 8 44 67 4.4
  Hearing 3 32 54 2.3 DNA repair 16 134 195 4.2
  G2/M transition of mitotic cell cycle 3 34 40 2.2 Regulation of translational initiation 5 26 30 3.6
  Anti-apoptosis 4 53 71 2.1 Di-, trivalent inorganic cation transport 8 66 102 3.0
  Transcription 38 1025 1992 2.0 Glycogen metabolism 4 24 25 2.9
18 hours after RE Protein amino acid phosphorylation 60 383 735 4.7 Peripheral nervous system development 5 11 12 5.5
  Regulation of cell cycle 42 248 294 4.5 Glycosphingolipid biosynthesis 3 5 5 5.0
  Anti-apoptosis 12 53 71 3.5 Antigen processing, endogenous antigen via MHC class I 3 6 11 4.5
  Mitochondrion organization and biogenesis 5 15 23 3.3 Iron transport 4 10 21 4.5
  Protein-mitochondrial targeting 4 11 19 3.2 Glutamine family amino acid catabolism 4 13 19 3.7
  L-Amino-acid transport 3 7 9 3.1 Male gonad development 3 9 12 3.4
Diurnal Regulation of transcription, DNA-dependent 46 938 1852 3.7 Regulation of protein biosynthesis 3 7 12 5.7
  Cell differentiation 7 68 109 3.6 Non-selective vesicle transport 7 57 63 3.7
  Response to stress 24 452 566 3.0 Actin cytoskeleton organization and biogenesis 3 15 23 3.5
  Hemopoiesis 3 22 28 2.9 Cell-cycle arrest 5 37 53 3.4
  Oncogenesis 14 253 282 2.4 Main pathways of carbohydrate metabolism 7 69 100 3.1
  Nucleic acid metabolism 61 1570 2905 2.3 Tricarboxylic acid cycle 3 20 23 2.8
  1. Filtered genes (p < 0.05) were analyzed with MAPPFinder to determine the biological processes that were regulated in each comparison. C, number of genes changed; M, number of genes represented on chip in a process; T, number of genes in the Gene Ontology (GO) process: Z, significance Z-score value. The top six, non-redundant GO terms are shown for each comparison